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Normal Pacinian corpuscles in the hand: radiology-pathology correlation in a cadaver study
Nicholas G Rhodes1, Naveen S Murthy2, Nirusha Lachman3
1Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA. rhodes.nicholas@mayo.edu.
Skeletal Radiology
|May 10, 2019
Summary
Magnetic Resonance Imaging (MRI) can identify normal Pacinian corpuscles in the hand. These specialized nerve endings appear as T2-hyperintense nodules on MRI, aiding in accurate anatomical identification.
Area of Science:
- Anatomy
- Radiology
- Histology
Background:
- Pacinian corpuscles are mechanoreceptors crucial for tactile sensation.
- Accurate identification of Pacinian corpuscles is important for understanding hand anatomy and potential pathologies.
Purpose of the Study:
- To prospectively identify normal Pacinian corpuscles using Magnetic Resonance Imaging (MRI).
- To confirm MRI findings through microdissection and histological analysis in a cadaver model.
Main Methods:
- A cadaveric hand specimen underwent 3-T MRI with skin markers.
- Subcutaneous nodules presumed to be Pacinian corpuscles were localized, sized, and their depths recorded.
- Microdissection and histological evaluation were performed to confirm findings.
Main Results:
- MRI revealed 11 T2-hyperintense palmar subcutaneous nodules near metacarpophalangeal joints.
- Eight nodules confirmed as normal Pacinian corpuscles via histology.
- No corpuscles were found in areas without nodules on MRI.
Conclusions:
- Normal Pacinian corpuscles appear as T2-hyperintense nodules on MRI.
- These nodules are typically round or oval and located in the palm around the metacarpophalangeal joints.
- MRI findings should not be confused with pathological conditions.
Keywords:
Dermal anatomyHandHypodermal anatomyLamellar corpuscleMRIMechanoreceptorPacinian corpuscleTouch receptorVater–PaciniMore Related Videos
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