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Updated: Jan 25, 2026

A Micropatterning Assay for Measuring Cell Chirality
Published on: March 11, 2022
Recognition Mechanisms of Chiral Selectors: An Overview
1Department of Pharmaceutical Chemistry, University of Jena, Jena, Germany. gerhard.scriba@uni-jena.de.
Abstract:
Stereospecific recognition of chiral molecules plays an important role in nature as the basis of the interaction of chiral bioactive compounds with the chiral target structures. In separation sciences such as chromatographic and capillary electromigration techniques, interactions between chiral analytes and chiral selectors, i.e., the formation of transient diastereomeric complexes in thermodynamic equilibria, are the basis for chiral separations. Due to the large structural variety of chiral selectors, different structural features contribute to the overall chiral recognition process. This introductory chapter briefly summarizes the present understanding of the structural enantioselective recognition processes for various types of chiral selectors.
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