Related Experiment Video
Updated: Jan 25, 2026

Synthesis of Programmable Main-chain Liquid-crystalline Elastomers Using a Two-stage Thiol-acrylate Reaction
Published on: January 19, 2016
Quantitation of Total and Free Thiol Angiotensinogen as a Prognostic Marker for Preeclampsia
M Qi1,2, James C Weaver2,3, S Rahgozar4
1Department of Infectious Diseases, Immunology and Sexual Health, St George Public Hospital, Sydney, NSW, Australia.
Abstract:
Angiotensinogen mediates an important role in the pathophysiology of preeclampsia, a disorder of pregnancy characterized by hypertension and proteinuria usually after 20 weeks of gestation. Angiotensinogen is found in two distinct posttranslational forms in the plasma, an oxidized and a reduced (free thiol) form. Higher levels of the oxidized form are associated with an increased risk of preeclampsia. We have developed novel ELISA assays to quantitate the levels of total and free thiol angiotensinogen allowing for calculation of the amount of oxidized angiotensinogen species. We describe the methodology for performing these assays.
More Related Videos
05:30Trophoblast Cell Recovery from Angiogenesis-Tube Formation Assay for Differentiation Marker Expression Analysis
Published on: November 8, 2024
08:47Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates
Published on: March 6, 2019
Related Concept Videos
Preparation and Reactions of Thiols
Structure and Nomenclature of Thiols and Sulfides
Total Voids in Concrete
Total Internal Reflection Fluorescence Microscopy
Static, Stagnation, Dynamic and Total Pressure
Quantitative Analysis
In quantitative analysis, two key measurements are made: the sample quantity and a property proportional to the amount of the analyte (the substance being analyzed). This forms the basis of the...