Related Experiment Video
Updated: May 31, 2026
10:32
Assessment of Sensorimotor Function in Mouse Models of Parkinson's Disease
Published on: June 17, 2013
Social role functioning in Parkinson's disease: A mixed-methods systematic review.
Kate Perepezko1,2, Jared T Hinkle1,3, Melissa D Shepard1
1Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
International Journal of Geriatric Psychiatry
|May 10, 2019
Summary
Parkinson's disease (PD) significantly impacts social roles and daily life, leading to withdrawal and relationship difficulties. Conventional treatments offer limited improvement in social functioning for individuals with PD.
Area of Science:
- Neurology
- Social Science
- Gerontology
Background:
- Parkinson's disease (PD) is a progressive neurodegenerative disorder.
- PD significantly impairs activities of daily living and social functioning.
- Changes in social roles affect employment, relationships, and overall quality of life.
Purpose of the Study:
- To systematically review the literature on social roles and functioning in Parkinson's disease.
- To understand how PD impacts individuals' social engagement and relationships.
- To identify challenges and inform future interventions for PD patients.
Main Methods:
- A mixed-methods systematic review was conducted.
- Literature search across five databases identified 51 relevant studies.
- Data were aggregated and analyzed to create a narrative summary.
Main Results:
- Parkinson's disease leads to withdrawal from social roles and functional deficits.
- PD symptoms like tremor and neuropsychiatric issues disrupt relationships and employment.
- Conventional PD therapies show minimal positive impact on social role functioning.
Conclusions:
- Parkinson's disease profoundly affects social functioning and roles.
- Interventions such as couple counseling and recreational activities may be beneficial.
- Further research is needed to develop effective strategies to support social well-being in PD.
More Related Videos
Related Concept Videos
01:37Neural Regulation
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
01:15Parkinson's Disease: Overview
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is to...
01:24Parkinson's Disease: Treatment
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
01:24Parkinson Disease l: Introduction
Parkinson’s disease is a chronic, progressive neurodegenerative disorder that primarily affects movement. It is characterized by motor symptoms such as resting tremors, muscle rigidity, bradykinesia (slowness of movement), and postural instability. Patients may notice hand tremors at rest, stiffness during movement, or a shuffling gait. In addition to motor features, non-motor symptoms include sleep disturbances, mood and behavioral changes, constipation, and cognitive impairment, all of which...
01:24Parkinson Disease ll: Pathophysiology
Parkinson disease (PD) is a progressive neurodegenerative disorder primarily affecting movement, with additional non-motor features. Its pathophysiology involves complex interactions among genetic susceptibility, environmental exposures, and cellular dysfunction, including dopaminergic neuron loss, protein aggregation, and mitochondrial impairment.Selective NeurodegenerationA key feature is the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to reduced...
01:11Alterations in Muscle Tone lll
Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...