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Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
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[Percutaneous treatment of chronic total coronary occlusion]

P Maréchal1, L Davin1, N Lhoest2

  • 1Service de Cardiologie, CHU Liège, Belgique.

Revue Medicale De Liege
|May 10, 2019
PubMed

Insights

Percutaneous treatment for chronic total occlusion (CTO) is increasingly viable, improving quality of life and enabling complete revascularization. Further randomized studies are needed to confirm benefits on survival and heart function.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology

Background:

  • Chronic total occlusion (CTO) was historically undertreated due to high complication risks.
  • CTO presence often dictated referral to surgical revascularization or optimized medical therapy.

Purpose of the Study:

  • To discuss the rationale for percutaneous revascularization of CTO.
  • To review patient selection criteria based on clinical and angiographic data.

Main Methods:

  • Review of recent technical advancements in percutaneous coronary intervention (PCI) for CTO.
  • Analysis of clinical and angiographic factors for patient selection.

Main Results:

  • Technical progress and specific tools have improved CTO percutaneous treatment feasibility.
  • Benefits on quality of life and complete revascularization are well-demonstrated.
  • Impact on survival and left ventricular function requires confirmation via prospective randomized trials.

Conclusions:

  • Percutaneous CTO revascularization is evolving, offering significant quality of life improvements.
  • Careful patient selection is crucial for successful outcomes.
  • Further evidence from randomized trials is needed to solidify its role in improving long-term survival and cardiac function.

Keywords:
Percutaneous coronary interventionQuality of liveChronic total coronary occlusion

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