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Updated: Jan 25, 2026

Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis
Published on: January 4, 2019
Chronic ischial tuberosity avulsion nonunion fracture treated with a platelet-rich plasma injection as a bone graft
Cleo D Stafford1, Ricardo E Colberg2, Alexander L Nourse3
1Department of Orthopaedics & Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.
Abstract:
We present a case of an 18-year-old with a 2-year history of buttock pain who failed extensive treatment for a perceived hamstring strain. Upon evaluation, he was diagnosed with an ischial tuberosity nonunion avulsion fracture. The patient underwent bone grafting via an ultrasound guided leukocyte rich platelet-rich plasma injection followed by the use of a bone stimulator to enhance the bone healing. At 3 months, he was asymptomatic and had radiographic evidence of excellent bone healing. He remained asymptomatic at 1 year and had resumed full activities. This case report is the first in the literature to describe the treatment of a chronic ischial tuberosity nonunion avulsion fracture with the use of platelet-rich plasma as a bone graft.
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