Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blind Procedures02:07

Blind Procedures

13.4K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
13.4K
Blinding01:11

Blinding

3.8K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
3.8K
Negative Regulator Molecules01:23

Negative Regulator Molecules

38.3K
Positive regulators allow a cell to advance through cell cycle checkpoints. Negative regulators have an equally important role as they terminate a cell’s progression through the cell cycle—or pause it—until the cell meets specific criteria.
38.3K
Contact-dependent Signaling01:19

Contact-dependent Signaling

46.9K
Contact-dependent signaling, as the name suggests, requires that communicating cells be in direct contact with each other. This is achieved either through receptor-ligand interactions or by specialized cytoplasmic channels that allow the flow of small molecules between cells. In animal cells, channels called gap junctions facilitate contact-dependent signaling in certain tissues, whereas, plasmodesmata perform a similar function in plants.
Gap Junctions
In animal cells, gap junctions are formed...
46.9K
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

403
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
403
Contact Angle01:13

Contact Angle

18.3K
When a solid is dipped inside a liquid, the liquid surface becomes curved near the contact. For some solid–liquid interfaces, the liquid is pulled up along the solid, while for others, the liquid surface is convex or depressed near the solid surface. This phenomenon can be explained using the concept of cohesive and adhesive forces.
The adhesive force is the molecular force between molecules of different materials, that is, between the molecules of the solid and the liquid. The cohesive...
18.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A dual-function host-guest antioxidant system for synergistic treatment of diquat poisoning.

RSC advances·2026
Same author

EECFS: Efficient Ensemble Causal Feature Selection for High-Dimensional Molecular Data.

Journal of chemical information and modeling·2026
Same author

Structural network dysfunction and aberrant SC-FC coupling correlate with central post-stroke pain of thalamic origin.

The journal of pain·2026
Same author

Obinutuzumab treatment for antineutrophil cytoplasmic antibody-associated vasculitis.

Frontiers in immunology·2026
Same author

Contrasting greenhouse gas fluxes in a city river-lake continuum: CH<sub>4</sub> diffusive emissions offset by N<sub>2</sub>O sequestration.

Environmental research·2026
Same author

AI Versus Human-Delivered Online Cognitive Behavioral Therapy for Anxiety Symptoms in Young Adults: A Randomized Controlled Trial.

Healthcare (Basel, Switzerland)·2026

Related Experiment Video

Updated: Jan 25, 2026

Semi-automated Optical Heartbeat Analysis of Small Hearts
12:10

Semi-automated Optical Heartbeat Analysis of Small Hearts

Published on: September 16, 2009

12.8K

Blind Source Separation on Non-Contact Heartbeat Detection by Non-Negative Matrix Factorization Algorithms.

Chen Ye, Kentaroh Toyoda, Tomoaki Ohtsuki

    IEEE Transactions on Bio-Medical Engineering
    |May 10, 2019
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a novel blind source separation (BSS) method using non-negative matrix factorization (NMF) to accurately estimate heart rate (HR) from radar signals, overcoming motion and respiration interference.

    More Related Videos

    Anesthesia-free Heartbeat Measurements in Freely Moving Zebrafish
    03:57

    Anesthesia-free Heartbeat Measurements in Freely Moving Zebrafish

    Published on: April 18, 2025

    1.1K
    How to Detect Amygdala Activity with Magnetoencephalography using Source Imaging
    10:48

    How to Detect Amygdala Activity with Magnetoencephalography using Source Imaging

    Published on: June 3, 2013

    22.7K

    Related Experiment Videos

    Last Updated: Jan 25, 2026

    Semi-automated Optical Heartbeat Analysis of Small Hearts
    12:10

    Semi-automated Optical Heartbeat Analysis of Small Hearts

    Published on: September 16, 2009

    12.8K
    Anesthesia-free Heartbeat Measurements in Freely Moving Zebrafish
    03:57

    Anesthesia-free Heartbeat Measurements in Freely Moving Zebrafish

    Published on: April 18, 2025

    1.1K
    How to Detect Amygdala Activity with Magnetoencephalography using Source Imaging
    10:48

    How to Detect Amygdala Activity with Magnetoencephalography using Source Imaging

    Published on: June 3, 2013

    22.7K

    Area of Science:

    • Biomedical Engineering
    • Signal Processing
    • Radar Technology

    Background:

    • Non-contact heart rate (HR) monitoring using Doppler radar is challenged by noise from respiration and body motion.
    • Accurate HR estimation is crucial for various health and wellness applications.

    Purpose of the Study:

    • To propose a blind source separation (BSS) approach for mitigating noise in Doppler radar signals for HR monitoring.
    • To enhance the resolution of heartbeat spectrum estimation using sparse spectrum reconstruction.

    Main Methods:

    • Utilized non-negative matrix factorization (NMF) algorithms for BSS to decompose mixed radar signals into distinct sources, including heartbeat.
    • Employed hierarchical clustering to learn basis spectra (BS) and applied sparse NMF variants (sparse NMF, weighted sparse NMF) to exploit temporal sparsity of heartbeat signals.
    • Developed a BSS approach with advantages including unsupervised learning via clustering, a compact demixing architecture, and single-channel input requirement.

    Main Results:

    • The proposed BSS method effectively mitigates noise interference in Doppler radar signals.
    • Achieved high-resolution heartbeat spectrum estimation through sparse spectrum reconstruction.
    • Demonstrated superior precision and robustness in HR estimation compared to existing methods, even during activities like typing.

    Conclusions:

    • The proposed BSS approach offers a significant advancement in non-contact HR monitoring accuracy and reliability.
    • This method provides a robust solution for HR estimation in the presence of physiological and motion artifacts.
    • The technique shows promise for practical applications requiring precise, unobtrusive heart rate tracking.