Fahr's Disease With Intracerebral Hemorrhage at the Uncommon Location: A Case Report

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Baek Hee Jang1, Seong Wook Son1, Chung Reen Kim1

  • 1Department of Physical Medicine and Rehabilitation, Ulsan University Hospital, Ulsan, Korea.

Annals of Rehabilitation Medicine
|May 11, 2019
PubMed

Insights

Fahr's disease, a rare neurologic condition, involves brain calcification. This case highlights an unusual hypertensive hemorrhage location, potentially due to calcification in common hemorrhage sites.

Area of Science:

  • Neurology
  • Radiology
  • Genetics

Background:

  • Fahr's disease (FD) is a rare neurologic disorder characterized by symmetric, bilateral intracerebral calcification.
  • It often presents with diverse neurological symptoms, making diagnosis challenging.

Observation:

  • A 65-year-old woman presented with gait disturbance, altered mentality, and visual field defects.
  • Brain CT revealed spontaneous intracranial hemorrhage and bilateral intracerebral calcification.
  • Laboratory tests indicated hypoparathyroidism, and her son also had similar calcifications, confirming FD.

Findings:

  • The patient had hypertension, a potential cause of hemorrhage.
  • However, the hemorrhage occurred in an uncommon parieto-occipital location, away from heavily calcified areas.
  • Massive calcification in the basal ganglia may have prevented hemorrhage in typical locations, redirecting it elsewhere.

Implications:

  • This case expands the understanding of Fahr's disease presentation and potential hemorrhage patterns.
  • It suggests that extensive intracranial calcification might influence the location of hypertensive hemorrhages.
  • Further research is needed to elucidate the relationship between calcification burden and hemorrhage site in FD.

Keywords:
Idiopathic basal ganglia calcification 1Intracranial hemorrhages

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