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Related Experiment Video

Updated: Jan 25, 2026

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

Behavioral and Emotional Difficulties after Pediatric Concussion.

Alice Gornall^1,2, Michael Takagi^1,3, Cathriona Clarke¹

¹Murdoch Children's Research Institute, Melbourne, Victoria, Australia.

Journal of Neurotrauma

|May 11, 2019

Summary

Pediatric concussion often causes temporary behavior problems that improve over time. However, older females may experience persistent internalizing issues post-concussion, needing targeted interventions.

Keywords:

CBCL behavior problems concussion recovery pediatrics

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Area of Science:

Pediatric neurology
Child psychology
Public health

Background:

Pediatric concussion is a significant public health issue.
Behavioral problems are common after concussion and may affect recovery.
Limited understanding exists on how behavior influences recovery in children and adolescents.

Purpose of the Study:

To investigate changes in behavioral and emotional functioning in children and adolescents following concussion.
To explore the impact of age and sex on post-concussion behavioral recovery.

Main Methods:

Prospective longitudinal cohort study of 231 children (ages 5 to <18) with concussion.
Data collected from Emergency Department (ED) of a tertiary children's hospital.
Child Behavior Checklist (CBCL) administered at 2 weeks (acute) and 3 months (post-acute) post-injury.

Main Results:

Significant reduction in internalizing, externalizing, and total behavior problems at 3 months compared to 2 weeks post-injury.
A significant interaction between age and sex was observed.
Older females showed higher rates of internalizing and total behavior problems as age increased.

Conclusions:

Pediatric concussion is linked to temporary behavioral disturbances that generally improve within months.
Older females may face a higher risk of persistent internalizing problems several months post-concussion.
Targeted clinical interventions may be necessary for at-risk female adolescents.