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Isolation and Transplantation of Hematopoietic Stem Cells HSCs
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Psychological Considerations in Hematopoietic Stem Cell Transplantation
Hermioni L Amonoo1, Christina N Massey2, Melanie E Freedman2
1Dana Farber Cancer Institute, Department of Psychosocial Oncology, Brookline, MA; Brigham and Women's Hospital, Boston, MA; Department of Psychiatry, Harvard Medical School, Boston, MA.
Psychosomatics
|May 11, 2019
Summary
Hematopoietic stem cell transplantation (HSCT) patients face significant psychological distress impacting recovery. Effective management of these challenges is crucial for improved patient outcomes and reduced complications.
Area of Science:
- Transplantation Medicine
- Psychiatry
- Oncology
Background:
- Hematopoietic stem cell transplantation (HSCT) has advanced, reducing mortality but leaving patients vulnerable to psychological distress.
- This distress negatively affects recovery, function, health outcomes, and increases risks like graft-versus-host disease.
- Early assessment and management of psychological symptoms are vital for treatment engagement and superior health outcomes.
Purpose of the Study:
- To review the psychological challenges associated with HSCT.
- To suggest management strategies for psychiatric consultants caring for HSCT patients.
- To provide a framework for addressing the mental health needs of this population.
Main Methods:
- A narrative review of published literature.
- Searches conducted in PubMed, PsycInfo, and Scopus databases.
- Focused on common psychological challenges, vulnerability factors, and interventions in HSCT.
Main Results:
- HSCT hospitalization involves distinct phases with common psychological issues like depression, delirium, and PTSD.
- An approach to psychiatric consultations during HSCT hospitalization is proposed.
- Practical interventions for managing psychological challenges in HSCT patients are discussed.
Conclusions:
- Pharmacological and behavioral interventions show success in managing psychosocial challenges post-HSCT.
- Further research is needed on optimal psychiatric assessment tools and treatment strategies.
- Long-term psychiatric care is essential for addressing comorbidities in the growing HSCT patient population.
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