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Updated: Jan 25, 2026
11:35
The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
58.7K
Slowed articulation rate is associated with information processing speed decline in multiple sclerosis: A pilot
Lucie Friedova1, Jan Rusz2, Jiri Motyl1
1Department of Neurology and Center of Clinical Neuroscience, First Faculty of Medicine, Charles University and General University Hospital, Katerinska 30, 120 00 Prague 2, Czech Republic.
Summary
Slowed speech articulation in multiple sclerosis (MS) patients is linked to cognitive decline. Objective speech analysis can help detect processing speed impairments in MS.
Area of Science:
- Neurology
- Speech-Language Pathology
- Cognitive Science
Background:
- Cognitive and speech impairments are common in multiple sclerosis (MS).
- The relationship between articulation rate and cognitive function in MS is not well understood.
Purpose of the Study:
- To examine the association between articulation rate characteristics and processing speed in MS patients.
- To evaluate the utility of objective speech analysis for detecting cognitive decline in MS.
Main Methods:
- 122 MS patients completed speaking tasks and cognitive assessments (Symbol Digit Modalities Test, Paced Auditory Serial Addition Test-3).
- Linear regression and receiver operating characteristic (ROC) curves were used to analyze the relationship between articulation rate and processing speed.
Main Results:
- A significant association was found between articulation rate and cognitive measures (rho = 0.45–0.58).
- Faster reading speed correlated with higher scores on cognitive tests.
- Articulation rate measures showed good predictive accuracy (AUC 0.67–0.79) for processing speed impairment.
Conclusions:
- Slowed articulation rate is a strong indicator of processing speed decline in MS.
- Objective speech analysis can effectively identify MS patients with cognitive deficits.
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