Related Experiment Video
Updated: Jan 25, 2026

Surgical Techniques to Optimize Ovarian Reserve during Laparoscopic Cystectomy for Ovarian Endometrioma
Published on: January 22, 2022
Impact of Anaesthetist Volume on Radical Cystectomy Outcomes
Ibrahim Jubber1, Karl H Pang1, Ruth Groves2
1Academic Urology Unit, University of Sheffield, Sheffield, UK.
Background:
Radical cystectomy (RC) is a gold standard treatment for aggressive bladder cancer. Higher surgical volumes through centralisation are associated with improved RC outcomes. The impact of anaesthetist experience and RC volume on outcomes is less clear.
Objective:
We sought to examine RC outcomes stratified by anaesthetist volume using a contemporary homogenous series.
Design, Setting, And Participants:
A retrospective analysis of a prospectively collected, single-surgeon database of RC patients over a 10-yr period.
Intervention:
Four hundred and fifty-three consecutive patients underwent RC, including 430 (95%) with anaesthetist annotation.
Outcome Measurements And Statistical Analysis:
Anaesthetists were stratified into low- (<10 cases) and high-volume (≥10 cases) classes. Primary outcomes were blood loss, transfusion rates, length of stay (LOS), and postoperative mortality.
Results And Limitations:
In total, 63 anaesthetists were included for analysis (median two RCs per anaesthetist). Of 63 anaesthetists, 56 (88.9%) and seven (11.1%) were classified, respectively, into low and high volume, and these provided cover for 110 (25.6%) and 320 (74.4%) patients, respectively. When comparing high- versus low-volume anaesthetists, there were shorter LOS (median [interquartile range {IQR}]: 10 [6-14] vs 12 [7-19] d, p = 0.008), lower blood loss (median [IQR]: 600 [384-1000] vs 800 [500-1275] ml, p<0.001), and lower transfusion rate (23/320, 7.2% vs 22/110, 20%; p < 0.001). There was no difference in disease-specific mortality, overall mortality, or readmission rates. In multivariable analysis, a high anaesthetist volume was independently associated with transfusion rate (odds ratio 0.24 [0.07-0.83], p = 0.02).
Conclusions:
Higher-volume anaesthetists have lower transfusion rates for RC patients. Whilst LOS and blood loss may also differ with experience, there is no difference in mortality after RC.
Patient Summary:
Radical cystectomy is a major operation. Experienced anaesthetists give fewer blood products to patients undergoing this operation. They may also help reduce blood loss and speed recovery. However, all other recovery measures were similar.
Related Concept Videos
Radical Reactivity: Nucleophilic Radicals
Radical Reactivity: Electrophilic Radicals
Predicting Reaction Outcomes
Impact of Groups on Groups
Outcomes of Glycolysis
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Radical Autoxidation

