Functional Improvement of Upper and Lower Extremity After Decompression and Neurolysis and Nerve Transfer in a

Rahul Kumar Nath1, Chandra Somasundaram1

  • 1Department of Surgical Research, Texas Nerve and Paralysis Institute, Houston, TX, USA.

Insights

Acute flaccid myelitis (AFM) is a polio-like illness causing paralysis. Surgical interventions like nerve decompression and transfer successfully restored limb function in a pediatric patient with EV-D68-induced AFM.

Area of Science:

  • Neurology
  • Pediatric Neurology
  • Infectious Diseases

Background:

  • Acute flaccid myelitis (AFM) is an emerging polio-like illness affecting children, causing rapid limb weakness and paralysis.
  • Enteroviruses (e.g., EV-68, EV-71), poliovirus, and West Nile virus are identified causes of AFM.
  • The US reported a significant increase in AFM cases in 2018, with 134 confirmed cases.

Observation:

  • A 5-year-old female presented with severe paralysis in all four extremities due to Enterovirus D68 (EV-D68) infection.
  • The patient experienced significant weakness in shoulders, biceps, and femoral/peroneal nerves, with the right shoulder function being severely impaired.
  • Conservative management was ineffective, and the patient also showed marked atrophy and weakness in the right quadriceps.

Findings:

  • The patient underwent surgical treatment, including decompression, neurolysis, and nerve transfer procedures.
  • Post-surgery, the patient demonstrated steady improvement in functional movements of all four extremities.

Implications:

  • Surgical interventions can effectively treat paralysis in acute flaccid myelitis patients.
  • This case highlights the potential of surgical repair for restoring limb function after EV-D68-related AFM.
  • Further research into surgical outcomes for AFM is warranted.

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