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Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers
Published on: October 29, 2021
Functional Improvement of Upper and Lower Extremity After Decompression and Neurolysis and Nerve Transfer in a
Rahul Kumar Nath1, Chandra Somasundaram1
1Department of Surgical Research, Texas Nerve and Paralysis Institute, Houston, TX, USA.
Insights
Acute flaccid myelitis (AFM) is a polio-like illness causing paralysis. Surgical interventions like nerve decompression and transfer successfully restored limb function in a pediatric patient with EV-D68-induced AFM.
Area of Science:
- Neurology
- Pediatric Neurology
- Infectious Diseases
Background:
- Acute flaccid myelitis (AFM) is an emerging polio-like illness affecting children, causing rapid limb weakness and paralysis.
- Enteroviruses (e.g., EV-68, EV-71), poliovirus, and West Nile virus are identified causes of AFM.
- The US reported a significant increase in AFM cases in 2018, with 134 confirmed cases.
Observation:
- A 5-year-old female presented with severe paralysis in all four extremities due to Enterovirus D68 (EV-D68) infection.
- The patient experienced significant weakness in shoulders, biceps, and femoral/peroneal nerves, with the right shoulder function being severely impaired.
- Conservative management was ineffective, and the patient also showed marked atrophy and weakness in the right quadriceps.
Findings:
- The patient underwent surgical treatment, including decompression, neurolysis, and nerve transfer procedures.
- Post-surgery, the patient demonstrated steady improvement in functional movements of all four extremities.
Implications:
- Surgical interventions can effectively treat paralysis in acute flaccid myelitis patients.
- This case highlights the potential of surgical repair for restoring limb function after EV-D68-related AFM.
- Further research into surgical outcomes for AFM is warranted.
Abstract:
BACKGROUND Acute flaccid myelitis is an emerging polio-like illness mostly affecting young children, characterized by rapid onset of extremity weakness and paralysis in 1 or more limbs. Certain viruses, including enteroviruses such as EV-68, EV-71, poliovirus, and West Nile virus, can cause this disorder. The largest known outbreak of EVD68 in the United States was in the summer of 2014, causing severe respiratory illness and acute flaccid myelitis, mainly in young children. Furthermore, the US Centers for Disease Control and Prevention noted an increase in the number of patients with clinical symptoms of acute flaccid myelitis in 2018, and 134 confirmed cases by December 2018 were reported in the USA. CASE REPORT The patient in our present study was a 5-year-old female who had significant weakness and paralysis in all 4 extremities due to acute flaccid myelitis. EV-D68 had caused this disorder in this patient in August 2014. Conservative management had not helped her condition. Specific areas of concern were both shoulders and biceps, and the femoral and peroneal nerves in both sides. Of these, the right shoulder function was the worst, at less than grade 3. The patient also had marked atrophy and weakness of the right quadricep muscles. The patient underwent surgical treatment and had steady improvements in all 4 extremity functional movements. CONCLUSIONS We demonstrated that decompression, neurolysis, and nerve transfer surgical procedures can be used successfully to correct the paralyzed upper and lower extremity movements in acute flaccid myelitis patients.
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