Program evaluation of an ORS and zinc scale-up program in 8 Nigerian states
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Published on: July 14, 2023
Felix Lam1, Ahmad Abdulwahab2, Jason Houdek2
1Clinton Health Access Initiative, Boston, Massachusetts, USA.
Insights
A program in Nigeria significantly increased the use of oral rehydration solution (ORS) and zinc for treating childhood diarrhea. This intervention improved treatment rates in both public and private healthcare sectors, saving young lives.
Area of Science:
- Public Health Interventions
- Pediatric Diarrheal Disease Management
- Health Systems Strengthening
Background:
- Diarrhea is a leading cause of mortality in Nigerian children under five.
- A multi-state program (2012-2017) by CHAI and the Nigerian Government targeted increased treatment with oral rehydration solution (ORS) and zinc.
- Interventions addressed demand, supply, and policy barriers across public and private sectors.
Purpose of the Study:
- To evaluate the impact of a comprehensive program on ORS and zinc treatment for childhood diarrhea in Nigeria.
- To assess changes in treatment rates and identify factors influencing ORS and zinc uptake.
Main Methods:
- Cross-sectional household surveys were conducted at baseline, midline, and endline in program states.
- Logistic regression models with generalized estimating equations were used to analyze changes in treatment practices.
- The study assessed treatment variations based on healthcare sector (public vs. private).
Main Results:
- Treatment with ORS increased from 38% at baseline to 55% at endline; combined ORS and zinc increased from 4% to 30%.
- The odds of receiving ORS treatment were 1.88 times higher at endline; odds of receiving ORS and zinc combined were 15.14 times higher.
- Significant improvements in ORS treatment probability were observed in both public (57% to 83%) and private (41% to 58%) sectors.
Conclusions:
- The implemented program led to a significant increase in the use of ORS and combined ORS and zinc for diarrhea treatment.
- The findings demonstrate the effectiveness of multi-faceted interventions in improving pediatric diarrheal disease management.
Background:
In Nigeria, diarrhea is the second leading killer of children under five. Between 2012-2017, the Clinton Health Access Initiative, Inc. (CHAI) and the Government of Nigeria implemented a comprehensive program in eight states aimed at increasing the percentage of children under five with diarrhea who were treated with zinc and oral rehydration solution (ORS). The program addressed demand, supply, and policy barriers to ORS and zinc uptake through interventions in both public and private sectors. The interventions included: (1) policy revision and partner coordination; (2) market shaping to improve availability of affordable, high-quality ORS and zinc; (3) provider training and mentoring; and (4) caregiver demand generation.
Methods:
We conducted cross-sectional household surveys in program states at baseline, midline, and endline and constructed logistic regression models with generalized estimating equations to assess changes in ORS and zinc treatment during the program period.
Results:
In descriptive analysis, we found 38% (95% CI = 34%-42%) received ORS at baseline and 4% (95% CI = 3%-5%) received both ORS and zinc. At endline, we found 55% (95% CI = 51%-58%) received ORS and 30% (95% CI = 27%-33%) received both ORS and zinc. Adjusting for other covariates, the odds of diarrhea being treated with ORS were 1.88 (95% CI = 1.46, 2.43) times greater at endline. The odds of diarrhea being treated with ORS and zinc combined were 15.14 (95% CI = 9.82, 23.34) times greater at endline. When we include the interaction term to investigate whether the odds ratios between the endline and baseline survey were modified by source of care, we found statistically significant results among diarrhea episodes that sought care in the public and private sector. Among cases that sought care in the public sector, the predictive probability of treatment with ORS increased from 57% (95% CI = 50%-65%) to 83% (95% CI = 79%-87%). Among cases that sought care in the private sector, the predictive probability increased from 41% (95% CI = 34%-48%) to 58% (95% CI = 54%-63%).
Conclusions:
Use of ORS and combined ORS and zinc for treatment of diarrhea significantly increased in program states during the program period.
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