Papillary meningioma: Diagnosis by intraoperative crush smear cytology

Shilpa P Tathe1, Sanjay N Parate1

  • 1Department of Pathology, Superspeciality Hospital and Government Medical College, Nagpur, Maharashtra, India.

Insights

Papillary meningioma, a rare WHO grade III tumor, shows distinct cytological features. Early diagnosis via intraoperative crush cytology aids in managing this aggressive brain tumor.

Area of Science:

  • Neuro-oncology
  • Cytopathology

Background:

  • Papillary meningioma is a rare, aggressive WHO grade III variant of meningioma, characterized by high recurrence and metastasis rates.
  • While histopathology is documented, cytomorphology of papillary meningioma is infrequently described.

Observation:

  • This report details a case of papillary meningioma diagnosed using intraoperative crush cytology, subsequently confirmed by histopathology.
  • Characteristic cytological findings include meningothelial features and a unique radial cell arrangement around hyalinized blood vessels.

Findings:

  • Intraoperative crush cytology can accurately diagnose papillary meningioma.
  • Distinct cytological features, particularly the vascular arrangement, are key diagnostic clues.

Implications:

  • Timely recognition of papillary meningioma through cytological evaluation is crucial for effective therapeutic strategies.
  • Integrating cytological findings with clinical and radiological data improves diagnostic accuracy and differentiation from other CNS papillary lesions.

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