Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Design Example: Calculating Safe Diameter for Wind-Exposed Disc01:17

Design Example: Calculating Safe Diameter for Wind-Exposed Disc

358
Assessing safety in wind-exposed installations is crucial to preventing potential failures. This example explores the calculation and design adjustments needed to mount a circular disc on a building facade, where wind forces are a primary concern. A 4-meter diameter disc was initially designed as an aesthetic feature facing winds at a velocity of 25 meters per second, with an air density of 1.25 kilograms per cubic meter. Given these conditions, the drag force on the disc was determined using...
358
Multiple Allele Traits01:49

Multiple Allele Traits

38.0K
The Concept of Multiple Allelism
38.0K
Non-LTR Retrotransposons03:18

Non-LTR Retrotransposons

13.3K
As the name suggests, non-LTR retrotransposons lack the long terminal repeats characteristic of the LTR retrotransposons. Additionally, both LTR and non-LTR retrotransposons use distinct mechanisms of mobilization. Non-LTR retrotransposons are further divided into two classes - Long interspersed nuclear elements (LINEs) and short interspersed nuclear elements (SINEs), both of which occur abundantly in most mammals, including humans. Some of the active non-LTR retrotransposons in humans are L1...
13.3K
Chromatin Position Affects Gene Expression02:35

Chromatin Position Affects Gene Expression

24.7K
Chromatin is the massive complex of DNA and proteins packaged inside the nucleus. The complexity of chromatin folding and how it is packaged inside the nucleus greatly influences  access to genetic information. Generally, the nucleus' periphery is considered transcriptionally repressive, while the cell's interior is considered a transcriptionally active area. 
Topologically Associated Domains (TADs)
The 3-dimensional positioning of chromatin in the nucleus influences the...
24.7K
Hypothalamic-Pituitary Axis01:37

Hypothalamic-Pituitary Axis

65.8K
The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
65.8K
RNA Stability01:53

RNA Stability

35.7K
Intact DNA strands can be found in fossils, while scientists sometimes struggle to keep RNA intact under laboratory conditions. The structural variations between RNA and DNA underlie the differences in their stability and longevity. Because DNA is double-stranded, it is inherently more stable. The single-stranded structure of RNA is less stable but also more flexible and can form weak internal bonds. Additionally, most RNAs in the cell are relatively short, while DNA can be up to 250 million...
35.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical and Radiological Outcomes of Skip-Level Cervical Disk Arthroplasty.

Neurosurgery·2026
Same author

Increasing autophagy activity suppresses <i>Helicobacter pylori</i> infection-related gastric cancer tumorigenesis both <i>in vitro</i> and <i>in vivo</i>.

American journal of cancer research·2026
Same author

Cryosurgical cranioplasty using autologous bone for metastatic skull lesion from hepatocellular carcinoma: illustrative case.

Journal of neurosurgery. Case lessons·2026
Same author

Taiwan practical consensus for evaluation and management of small-bowel bleeding.

Journal of the Chinese Medical Association : JCMA·2026
Same author

Gut microbiota profiles by LDL-C target achievement in statin-treated patients: A cross-sectional study.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2025
Same author

<i>Clostridium butyricum MIYAIRI 588</i> Reduces Colorectal Adenomatous Polyp Recurrence: A Randomized Crossover Trial.

Oncology research·2025

Related Experiment Video

Updated: Jan 25, 2026

A Mobile Outside-in Technique of Transforaminal Lumbar Endoscopy for Lumbar Disc Herniations
05:50

A Mobile Outside-in Technique of Transforaminal Lumbar Endoscopy for Lumbar Disc Herniations

Published on: August 7, 2018

12.3K

Cervical disc arthroplasty for less-mobile discs.

Tsung-Hsi Tu1,2,3, Chu-Yi Lee1,2, Chao-Hung Kuo1,2

  • 11Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital.

Journal of Neurosurgery. Spine
|May 11, 2019
PubMed
Summary
This summary is machine-generated.

Cervical disc arthroplasty (CDA) provides similar clinical improvements regardless of preoperative range of motion (ROM). Patients with less preoperative ROM experienced greater increases in motion after CDA but remained less mobile overall.

Keywords:
ACDF = anterior cervical discectomy and fusionASD = adjacent-segment degenerationCDACDA = cervical disc arthroplastyHO = heterotopic ossificationJOA = Japanese Orthopaedic AssociationNDI = Neck Disability IndexPLL = posterior longitudinal ligamentROMROM = range of motionVAS = visual analog scalecervical disc arthroplastyrange of motionsegmental mobility

More Related Videos

Dissection and Mounting of Drosophila Pupal Eye Discs
07:48

Dissection and Mounting of Drosophila Pupal Eye Discs

Published on: November 9, 2014

12.8K
Dissection and Immunostaining of Imaginal Discs from Drosophila melanogaster
10:10

Dissection and Immunostaining of Imaginal Discs from Drosophila melanogaster

Published on: September 20, 2014

27.6K

Related Experiment Videos

Last Updated: Jan 25, 2026

A Mobile Outside-in Technique of Transforaminal Lumbar Endoscopy for Lumbar Disc Herniations
05:50

A Mobile Outside-in Technique of Transforaminal Lumbar Endoscopy for Lumbar Disc Herniations

Published on: August 7, 2018

12.3K
Dissection and Mounting of Drosophila Pupal Eye Discs
07:48

Dissection and Mounting of Drosophila Pupal Eye Discs

Published on: November 9, 2014

12.8K
Dissection and Immunostaining of Imaginal Discs from Drosophila melanogaster
10:10

Dissection and Immunostaining of Imaginal Discs from Drosophila melanogaster

Published on: September 20, 2014

27.6K

Area of Science:

  • Neurosurgery
  • Orthopedic Surgery
  • Spinal Surgery

Background:

  • Cervical disc arthroplasty (CDA) successfully preserves motion, but outcomes based on preoperative range of motion (ROM) are not well-defined.
  • Previous trials included patients with adequate preoperative mobility (≥2°).
  • The impact of lower preoperative ROM on CDA outcomes requires further investigation.

Purpose of the Study:

  • To compare clinical and radiological outcomes of cervical disc arthroplasty (CDA) in patients with low versus high preoperative C5-6 range of motion (ROM).
  • To determine if preoperative ROM influences the success of motion preservation after CDA.

Main Methods:

  • Retrospective review of 60 patients undergoing C5-6 CDA for radiculopathy/myelopathy.
  • Patients were grouped by preoperative ROM: less-mobile (≤5°) and more-mobile (>5°).
  • Clinical outcomes (VAS, NDI, JOA) and radiological ROM were assessed over 2 years.

Main Results:

  • Both groups showed significant clinical improvement with no significant differences.
  • The less-mobile group had a greater increase in ΔROM (5.5° vs 0.1°, p=0.001) but less final segmental mobility (8.5° vs 11.7°, p=0.04).
  • Complication rates were similar between groups.

Conclusions:

  • Preoperative segmental mobility does not affect clinical outcomes after cervical disc arthroplasty (CDA).
  • Patients with less preoperative ROM achieve similar clinical success and greater motion increase post-CDA.
  • Despite greater motion increase, less-mobile discs remain less mobile postoperatively.