Related Experiment Video
Updated: Jan 25, 2026
07:11
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
6.8K
Combined phacoemulsification and microinvasive glaucoma surgery in comparison to phacoemulsification alone for open
Graham A Lee1,2,3, Ashley J Porter4, Roslyn A Vincent4
1City Eye Centre, Brisbane, QLD, Australia. eye@cityeye.com.au.
Eye (London, England)
|May 12, 2019
Summary
Combining microinvasive glaucoma surgery (MIGS) with phacoemulsification effectively lowers intraocular pressure and medication needs in open-angle glaucoma patients. These benefits are sustained long-term, with low complication rates for MIGS procedures.
Area of Science:
- Ophthalmology
- Glaucoma Management
- Surgical Innovation
Background:
- Microinvasive glaucoma surgery (MIGS) combined with phacoemulsification is increasingly used for glaucoma management.
- Open-angle glaucoma requires effective long-term treatment strategies to reduce intraocular pressure (IOP) and medication dependence.
Purpose of the Study:
- To compare the postoperative outcomes of phacoemulsification alone versus combined phacoemulsification with iStent or Hydrus MIGS devices.
- To evaluate the efficacy of MIGS in reducing intraocular pressure and medication usage in open-angle glaucoma patients.
Main Methods:
- A retrospective single-surgeon comparative case series included 297 eyes from 190 patients.
- Data were analyzed using linear mixed models, focusing on intraocular pressure (IOP) and medication count.
- Follow-up extended to two years post-surgery.
Main Results:
- All surgical groups achieved IOP reduction by six months, sustained to two years.
- Combined iStent and Hydrus groups showed greater medication reduction (0.7 and 1.1, respectively) compared to phacoemulsification alone (0.3).
- Postoperative complications related to MIGS device insertion were infrequent and resolved within one month.
Conclusions:
- Combining phacoemulsification with MIGS devices significantly reduces IOP and medication requirements in open-angle glaucoma patients.
- The benefits of combined surgery are sustained up to two years post-operation.
- MIGS implantation, when performed without intraoperative complications, presents a low risk of significant short-term adverse events.
Related Concept Videos
01:27Open Angle Glaucoma: Treatment
971
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
971
01:28Angle Closure Glaucoma: Treatment
1.2K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.2K
01:25Glaucoma: Overview
1.3K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.3K
01:13Contact Angle
18.3K
When a solid is dipped inside a liquid, the liquid surface becomes curved near the contact. For some solid–liquid interfaces, the liquid is pulled up along the solid, while for others, the liquid surface is convex or depressed near the solid surface. This phenomenon can be explained using the concept of cohesive and adhesive forces.
The adhesive force is the molecular force between molecules of different materials, that is, between the molecules of the solid and the liquid. The cohesive...
The adhesive force is the molecular force between molecules of different materials, that is, between the molecules of the solid and the liquid. The cohesive...
18.3K
02:57The Sense of Self: Reflected Self-Appraisal and Social Comparison
55.6K
According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
55.6K
01:13Angle of Twist: Problem Solving
764
An electric motor applies a torque of 700 N·m to an aluminum shaft, triggering a stable rotation. Two pulleys, B and C, are subjected to torques of 300 N·m and 400 N·m, respectively. The modulus of rigidity is provided as 25 GPa. With the knowledge of the length and diameter of each segment, the twist angle between the two pulleys can be computed. First, a section cut is made between pulleys B and C, and the cut cross-section is analyzed using a free-body diagram. Given that the torque...
764