Related Experiment Video
Updated: Aug 9, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
Performance of the 2WIN Photoscreener With "CR" Strabismus Estimation in High-Risk Patients
Stephanie L Arnold1, Andrew W Arnold1, Jacob H Sprano2
1Pacific Northwest University College of Osteopathic Medicine, Yakima, Washington, USA.
Purpose:
Accurate estimation of refractive error and ocular alignment is critical for identifying amblyopia risk factors. The 2WIN photoscreener (Adaptica) uses a novel infrared-transmitting occluder wand to quickly estimate intermittent deviations.
Design:
Reliability analysis.
Methods:
2WIN refraction was compared to dry and cycloplegic retinoscopy and Retinomax. 2WIN "CR" function with wand was compared to cover test.
Results:
371 patients aged 6 months to 63 years (median age 6 years) had refraction, and 2WIN yielded high degrees of correlation (Pearson product-moment) on linear regression for spherical equivalent (0.73-0.79), cylinder power (0.78-0.79), J0 vector (0.79-0.83), and J45 vector (0.64-0.67). Similar proportions of 2WIN and Retinomax were within target refraction values for spherical equivalent (70% [216/310] vs 69% [212/310]), cylinder power (94% [154/165] vs 90% [148/165]), and cylinder axis (69% [113/165] vs 71% [118/165]). 2WIN CR higher than 10 prism diopters (PD) correlated with cover test for constant and intermittent deviations (Pearson correlation 0.64-0.71). 2WIN + CR screened for 2003 American Association for Pediatric Ophthalmology and Strabismus amblyopia risk factors with 68% (965/96) sensitivity and 84% (70/83) specificity in preschool children with 53% (96/180) prescreening probability and 31% (55/177) developmental delays.
Conclusion:
The 2WIN correlated well with examination and Retinomax. The CR function reliably estimated constant and intermittent strabismus higher than 10 PD.

