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Updated: Jan 25, 2026

Human Blastocyst Biopsy and Vitrification
Published on: July 26, 2019
The first report of pregnancies following blastocyst automated vitrification in Europe
Mariabeatrice Dal Canto1, Clarissa Moutier1, Fausta Brambillasca1
1Biogenesi Reproductive Medicine Centre, InstituteClinici Zucchi, Monza, Italy.
Abstract:
Embryo cryopreservation is a valuable technique in assisted reproductive technology (ART) that increases cumulative pregnancy rates and allows postponement of embryo transfer in patients with undesirable uterine or clinical conditions. Although vitrification has been considered the most efficient method to freeze oocytes and embryos, it is time-consuming and highly operator-dependent. Gavi® is the first semi-automated machine for vitrification capable of controlling crucial variables such as temperature, volume, concentration and exposure time during the vitrification process. We report the first two pregnancies obtained with blastocysts cryopreserved with the Gavi® semi-automated vitrification system in Europe. These outcomes suggest that the utilization of semi-automated vitrification may contribute to improve the outcomes and laboratory logistics of fertility clinics.
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08:28Morphometric Protocol for the Objective Assessment of Blastocyst Behavior During Vitrification and Warming Steps
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