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Published on: October 16, 2021
Transcatheter Edge-to-Edge Repair for Primary (Degenerative) Mitral Regurgitation: Registries and Trials
Dhaval Desai1, Matthew J Price1
1Division of Cardiovascular Diseases, Scripps Clinic, 9898 Genesee Avenue, AMP-200, La Jolla, CA 92037, USA.
Abstract:
The MitraClip is the only approved transcatheter edge-to-edge repair device that is commercially available for the treatment of severe, symptomatic, primary (degenerative) mitral regurgitation in patients deemed to be at prohibitive risk by a heart team. Transcatheter edge-to-edge repair can be safely performed with a low rate of periprocedural adverse events despite a predominantly elderly patient population with multiple comorbidities. Transcatheter edge-to-edge repair is associated with improvement in mitral regurgitation severity; left ventricular dimensions and remodeling; heart failure rehospitalizations; and, in high-risk groups, an improvement in survival compared with medical therapy.
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