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Related Concept Videos

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IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
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Mitral Valve Prolapse II: Assessment and Management01:22

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IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
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The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
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The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
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Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Transcatheter Mitral Valve Replacement with Tendyne.

Hiroki Niikura1, Mario Gössl1, Paul Sorajja2

  • 1Valve Science Center, Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital, 920 East 28th Street, Minneapolis, MN 55407, USA.

Interventional Cardiology Clinics
|May 13, 2019
PubMed
Summary
This summary is machine-generated.

Transcatheter mitral valve replacement (TMVR) offers a new treatment for severe mitral regurgitation in high-risk patients. The Tendyne prosthesis shows promise as a safe and effective short-term alternative to surgery.

Keywords:
Mitral regurgitationTendyne valve prosthesisTranscatheter mitral valve replacement

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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Biomedical Engineering

Background:

  • Mitral regurgitation is a prevalent valvular heart disease in developed nations.
  • Severe mitral regurgitation poses significant risks, especially for patients ineligible for traditional surgery or transcatheter edge-to-edge repair.
  • Transcatheter mitral valve replacement (TMVR) presents a less invasive therapeutic option.

Purpose of the Study:

  • To evaluate the safety and efficacy of TMVR using the Tendyne prosthesis.
  • To assess TMVR as a treatment for patients with severe mitral valve disease who are high-risk surgical candidates.

Main Methods:

  • Utilized the Tendyne prosthesis for transcatheter mitral valve replacement.
  • Focused on short-term follow-up data.
  • Included high-risk patients with severe mitral valve disease.

Main Results:

  • The Tendyne TMVR demonstrated potential effectiveness in the short term.
  • The procedure was found to be safe for the studied patient group.
  • TMVR with Tendyne offers a viable alternative for specific patient populations.

Conclusions:

  • Transcatheter mitral valve replacement with the Tendyne prosthesis is a potentially safe and effective treatment for high-risk patients with severe mitral valve disease.
  • Short-term outcomes suggest TMVR is a promising alternative for patients unsuitable for conventional surgery or repair.
  • Further long-term studies are warranted to fully establish the role of TMVR in valvular heart disease management.