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Course of upper eyelid retraction in thyroid eye disease
Dong Cheol Lee1, Stephanie M Young2, Yoon-Duck Kim3
1Department of Ophthalmology, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, South Korea.
The British Journal of Ophthalmology
|May 13, 2019
Summary
Upper eyelid retraction (UER) in thyroid eye disease (TED) often improves naturally within 24 months. Factors like family history influence UER normalization, aiding treatment decisions.
Area of Science:
- Ophthalmology
- Endocrinology
Background:
- Thyroid eye disease (TED) can cause upper eyelid retraction (UER), impacting patient quality of life.
- Understanding the natural course of UER in TED is crucial for effective management.
Purpose of the Study:
- To evaluate the natural progression of UER in patients with TED.
- To identify factors influencing the course and resolution of UER.
Main Methods:
- Retrospective cohort study of 61 TED patients with UER.
- Analysis of margin reflex distance 1 (MRD1) changes over 24 months.
- Assessment of factors associated with UER normalization.
Main Results:
- Mean MRD1 decreased significantly over 24 months, indicating UER improvement.
- 49.4% of eyes showed normalized lid height by 24 months.
- Family history of TED was linked to a lower likelihood of UER normalization.
Conclusions:
- UER in TED often shows natural improvement over time.
- Knowledge of UER's natural history aids in optimizing patient management strategies.
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