Related Experiment Video
Updated: Jan 25, 2026

07:49
Isolating Stem Cells from Soft Musculoskeletal Tissues
Published on: July 5, 2010
13.9K
Soft Tissue Reconstruction with Diabetic Foot Tissue Loss
Todd A Hasenstein1, Timothy Greene1, Jennifer C Van2
1Temple University Hospital Podiatric Surgical Residency Program, 8th at Race Street, Philadelphia, PA 19107, USA.
Clinics in Podiatric Medicine and Surgery
|May 14, 2019
Summary
Diabetic foot disease treatments are advancing, yet surgeries remain reactive, often leading to amputation. This article focuses on minimizing tissue loss and reconstructing defects through detailed anatomical assessment.
Area of Science:
- Podiatric medicine
- Surgical anatomy
- Diabetology
Background:
- Despite advances in diabetic foot disease management, surgical interventions remain largely reactive.
- Patients frequently present with acute infections and tissue necrosis, necessitating emergency treatment.
- Current surgical approaches often result in significant soft tissue deficits and partial foot amputations.
Purpose of the Study:
- To shift surgical focus from reactionary debridement to minimizing initial tissue loss.
- To detail the anatomical structures at risk in the forefoot, midfoot, and rearfoot for diabetic foot disease.
- To provide a foundation for subsequent reconstruction strategies following debridement.
Main Methods:
- Anatomical assessment of the forefoot, midfoot, and rearfoot structures relevant to diabetic foot disease.
- Review of current surgical interventions and their outcomes regarding tissue loss.
- Literature synthesis on reconstructive techniques for diabetic foot defects.
Main Results:
- Identification of critical anatomical structures necessitating careful consideration during debridement.
- Emphasis on strategies to preserve viable tissue during initial surgical intervention.
- Outlined approach for defect reconstruction based on anatomical findings.
Conclusions:
- Minimizing initial soft tissue loss in diabetic foot disease is crucial for better outcomes.
- Detailed anatomical knowledge of the foot is essential for effective surgical planning.
- A proactive approach focusing on tissue preservation and reconstruction can improve patient management.
Related Concept Videos
Tissues
84.9K
Cells with similar structure and function are grouped into tissues. A group of tissues with a specialized function is called an organ. There are four main types of tissue in vertebrates: epithelial, connective, muscle, and nervous.
84.9K
Tissues
64.3K
Tissues are a group of cells that share a common embryonic origin. Microscopic observation reveals that the cells in a tissue share morphological features and are arranged in an orderly pattern to perform specific functions. From an evolutionary perspective, tissues appear in more complex organisms. Although there are many types of cells in the human body, they are organized into four broad categories of tissues: epithelial, connective, muscle, and nervous. Each of these categories is...
64.3K
Plant Cells and Tissues
65.4K
Plant tissues are collections of similar cells performing related functions. Different plant tissues will have their own specialized roles and can be combined with other tissues to form organs such as flowers, fruit, stem, and leaves. Two major types of plant tissue include meristematic and permanent tissue.
65.4K
Muscles of the Leg that Move the Foot and Toes
4.0K
The human leg comprises an intricate system of muscles that facilitate the movement of feet and toes. Within this system, the muscles are categorized into the anterior, lateral, and posterior compartments, each with a unique set of muscles carrying out specific functions.
Anterior Compartment
The anterior compartment includes muscles that contribute to the dorsiflexion of the foot. This compartment houses the tibialis anterior, extensor hallucis longus, and extensor digitorum longus muscles....
Anterior Compartment
The anterior compartment includes muscles that contribute to the dorsiflexion of the foot. This compartment houses the tibialis anterior, extensor hallucis longus, and extensor digitorum longus muscles....
4.0K
Plant Tissue Culture
40.4K
Plant tissue culture is widely used in both primary and applied science. Applications range from plant development studies to functional gene studies, crop improvement, commercial micropropagation, virus elimination, and conservation of rare species.
40.4K
Line Loss
518
The different configurations of source-load connections include wye (star) and delta connections. The relationship between line and phase voltages and currents varies depending on the configuration. When the source is supplying power, it is transmitted through the wires to the load, and during this transmission, some power is absorbed by the wires, leading to line loss.
Line loss impacts power delivery efficiency in a balanced three-phase circuit. The symmetry in such a circuit simplifies the...
Line loss impacts power delivery efficiency in a balanced three-phase circuit. The symmetry in such a circuit simplifies the...
518

