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Updated: Jan 25, 2026

Sequential In vivo Imaging of Osteogenic Stem/Progenitor Cells During Fracture Repair
Published on: May 23, 2014
Cell-Based Therapies for the Treatment of Fractures
Joseph Borrelli1, Gregory J Della Rocca2, Prism Schneider3
1Department of Orthopedic Surgery and Sports Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL.
Abstract:
Ongoing studies investigating fracture healing have uncovered and allowed investigators to gain a better understanding of where the variety of cells, which participate in this process, originate, and how they communicate as well as how they can be enhanced to successfully heal a fracture when the process has slowed or failed completely. This brief review will highlight some of the recent findings regarding the role the immune system in fracture healing and how these cells communicate with each other during the healing process. In addition, two 2 methods that have recently been shown to be promising techniques in supporting fracture when it stalls or reversing the process, when the fracture has failed to heal, will also be described.
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