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Cost effectiveness of routine postmortem histology.

W A Reid

    Journal of Clinical Pathology
    |April 1, 1987
    PubMed
    Summary

    Unselected postmortem histology is often unnecessary, with 46% of tissue samples showing no anticipated abnormalities. This practice is not cost-effective for diagnostic purposes, wasting significant resources on routine microscopic examination.

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    Area of Science:

    • Pathology
    • Medical Laboratory Science
    • Health Economics

    Background:

    • Postmortem histology is a standard diagnostic procedure.
    • The utility and cost-effectiveness of unselected tissue sampling require evaluation.

    Purpose of the Study:

    • To assess the diagnostic yield and cost-effectiveness of unselected postmortem histology.
    • To determine the proportion of tissue samples with clinically significant findings.

    Main Methods:

    • Retrospective analysis of 160 necropsy records.
    • Review of clinical and gross necropsy findings.
    • Evaluation of microscopic findings and their impact on diagnosis.

    Main Results:

    • 46% of tissue samples showed no clinically important abnormalities anticipated from gross findings.
    • Few microscopic findings altered the diagnosis.
    • Annual cost of processing unselected material estimated at £10,500, including MLSO salary.

    Conclusions:

    • Unselected postmortem histology is not cost-effective for diagnostic purposes.
    • Routine microscopic examination of all postmortem tissue samples may be inefficient.
    • Resource allocation in diagnostic pathology could be optimized.

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