Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Interference and Diffraction02:18

Interference and Diffraction

51.9K
Interference is a characteristic phenomenon exhibited by waves. When two electromagnetic waves interact with their peaks and troughs coinciding, a resulting wave with enhanced amplitude is produced. This is known as constructive interference. In this case, the two waves interacting are in phase with each other.
51.9K
RNA Interference01:23

RNA Interference

27.9K
RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...
27.9K
The Sense of Self: Reflected Self-Appraisal and Social Comparison02:57

The Sense of Self: Reflected Self-Appraisal and Social Comparison

55.6K
According to Charles Cooley, we base our image on what we think other people see (Cooley 1902). We imagine how we must appear to others, then react to this speculation. We don certain clothes, prepare our hair in a particular manner, wear makeup, use cologne, and the like—all with the notion that our presentation of ourselves is going to affect how others perceive us. We expect a certain reaction, and, if lucky, we get the one we desire and feel good about it. But more than that, Cooley...
55.6K
Interference and Decay01:16

Interference and Decay

442
Forgetting is a complex cognitive phenomenon influenced by several factors, among which interference and decay are particularly prominent. These processes explain why individuals often struggle to retrieve specific information from memory, leading to lapses in recall that can be observed in everyday situations.
Interference occurs when competing memories hinder the retrieval of particular information. It can be classified into two types: proactive and retroactive interference. Proactive...
442
Introduction to Special Senses01:26

Introduction to Special Senses

7.3K
Sensory receptors play an integral part in comprehending our external and internal environments. They receive diverse stimuli, converting them into the nervous system's electrochemical signals. This conversion occurs as the stimulus alters the sensory neuron's cell membrane potential, instigating the generation of an action potential. This action potential is subsequently transmitted to the central nervous system (CNS), which integrates with other sensory data or higher cognitive...
7.3K
Interference: Path Lengths01:10

Interference: Path Lengths

1.9K
Consider two sources of sound, that may or may not be in phase, emitting waves at a single frequency, and consider the frequencies to be the same.
Two special sources may be considered when they are in phase. This can be easily achieved by feeding the two sources from the same source. An example would be synchronizing the two speakers by feeding them with the same source, such as the sound waves produced by a tuning fork. This setup ensures that the two sources have the same frequency and are...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Engineered ATP-Loaded Extracellular Vesicles Derived from Mesenchymal Stromal Cells: A Novel Strategy to Counteract Cell ATP Depletion in an In Vitro Model.

International journal of molecular sciences·2025
Same author

Disruption of exploratory behavior and olfactory memory in cockroaches exposed to sublethal doses of the neonicotinoid Thiamethoxam.

Pesticide biochemistry and physiology·2024
Same author

Rapid diagnosis and recurrence prediction of choledocholithiasis disease using raw bile with machine learning assisted SERS.

Talanta·2024
Same author

Highly Sensitive Surface-Enhanced Raman Scattering Detection of Hydroxyl Radicals in Water Microdroplets Using Phthalhydrazide/Ag Nanoparticles Nanosensor.

Environmental science & technology·2024
Same author

The Benefits of the Mediterranean Diet on Inflamm-Aging in Childhood Obesity.

Nutrients·2024
Same author

Exosomal-miRNas expression and growth factors released by mononuclear cells of CLAD patients in response to extracorporeal photopheresis.

Journal of translational medicine·2024

Related Experiment Video

Updated: Jan 25, 2026

Fabrication of Periodic Gold Nanocup Arrays Using Colloidal Lithography
08:21

Fabrication of Periodic Gold Nanocup Arrays Using Colloidal Lithography

Published on: September 2, 2017

7.6K

Large Area Nanohole Arrays for Sensing Fabricated by Interference Lithography.

Chiara Valsecchi1, Luis Enrique Gomez Armas2, Jacson Weber de Menezes3

  • 1Engineering Department, Universidade Federal do Pampa, Alegrete 97546-550, RS, Brazil. chiaravalsecchi@unipampa.edu.br.

Sensors (Basel, Switzerland)
|May 15, 2019
PubMed
Summary

Interference lithography fabricates large-area nanohole arrays for efficient sensing. This method offers high sensitivity, surpassing expensive nanofabrication techniques for bulk sensing applications.

Keywords:
biological sensing and sensorsholographynanostructuresoptics at surfacessubwavelength structuressurface plasmons

More Related Videos

Polymeric Microneedle Array Fabrication by Photolithography
08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

12.9K
Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array
07:19

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Published on: September 7, 2018

9.0K

Related Experiment Videos

Last Updated: Jan 25, 2026

Fabrication of Periodic Gold Nanocup Arrays Using Colloidal Lithography
08:21

Fabrication of Periodic Gold Nanocup Arrays Using Colloidal Lithography

Published on: September 2, 2017

7.6K
Polymeric Microneedle Array Fabrication by Photolithography
08:15

Polymeric Microneedle Array Fabrication by Photolithography

Published on: November 17, 2015

12.9K
Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array
07:19

Fabrication of a Multiplexed Artificial Cellular MicroEnvironment Array

Published on: September 7, 2018

9.0K

Area of Science:

  • Nanofabrication
  • Optical Sensing
  • Materials Science

Background:

  • Various nanofabrication techniques exist for sensor development.
  • Existing methods like focused ion beam milling (FIB) and e-beam lithography (EBL) can be costly and time-consuming.
  • There is a need for scalable and efficient methods for producing nano-patterned substrates.

Purpose of the Study:

  • To explore interference lithography for fabricating large-area nanohole arrays in metal films.
  • To optimize nanohole array parameters (size, periodicity, film thickness) for enhanced sensing performance.
  • To evaluate the efficiency and sensitivity of interference lithography for bulk sensing applications.

Main Methods:

  • Fabrication of large-area nanohole arrays using interference lithography.
  • Characterization of transmission spectra of 1 cm² substrates.
  • Systematic variation of hole size, periodicity, and film thickness.
  • Bulk sensing experiments to determine sensitivity.

Main Results:

  • Interference lithography successfully produced large-area nanohole arrays.
  • Optimized arrays demonstrated high sensitivity for bulk sensing.
  • Achieved sensitivity of approximately 1000 nm/RIU with visible range periodicity.
  • Performance exceeded previously reported near-infrared (NIR) sensing capabilities.

Conclusions:

  • Interference lithography is an efficient, flexible, and scalable method for nanohole array fabrication.
  • This technique provides a cost-effective alternative to expensive and time-consuming nanofabrication methods.
  • The developed nanohole arrays show significant potential for high-performance bulk sensing applications.