Hip fractures in patients with chronic kidney disease admitted to Victorian hospitals

Nisha Rao1, Nigel D Toussaint1,2

  • 1Department of Nephrology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.

Insights

Patients with chronic kidney disease (CKD) have higher hip fracture rates and mortality. This study highlights the need for better understanding of fracture epidemiology in CKD patients in Australia.

Area of Science:

  • Epidemiology
  • Nephrology
  • Gerontology

Background:

  • Limited epidemiological data exists on fracture incidence in Australian chronic kidney disease (CKD) patients.
  • Hip fractures represent a significant health burden, particularly in older populations.

Purpose of the Study:

  • To determine the incidence of hip fractures requiring hospitalization in patients with and without CKD in Victoria, Australia.
  • To analyze trends in hip fracture rates and associated comorbidities over a 10-year period.

Main Methods:

  • Utilized the Victorian Admitted Episodes Dataset from 2006-2015.
  • Identified hip fractures and comorbidities using ICD-9 and ICD-10 codes.
  • Compared fracture rates and mortality between patients with and without CKD.

Main Results:

  • 7.4% of 77,076 hip fracture hospital admissions had CKD as a comorbidity.
  • The proportion of hip fractures with CKD increased over the study period.
  • Mortality was significantly higher in the CKD cohort, associated with diabetes and ischemic heart disease.

Conclusions:

  • CKD is an important comorbidity associated with increased hip fracture hospitalization and mortality in Australia.
  • Further research is warranted to investigate the mechanisms and optimal management strategies for fractures in CKD patients.

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