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Updated: Jan 25, 2026

Preparation and Using Phantom Lesions to Practice Fine Needle Aspiration Biopsies
Published on: September 29, 2009
Percutaneous needle biopsy of retroperitoneal lesions: technical developments
Andrea Bevilacqua1, Fabiano Vito D'Amuri, Francesco Pagnini
1Department of Medicine and Surgery, Unit of Radiologic Science, University of Parma, Maggiore Hospital, Parma, Italy. f.pagnini90@gmail.com.
Percutaneous Needle Biopsy (PNB) is a minimally invasive procedure for obtaining tissue samples for diagnosis. It is a valuable tool for characterizing lesions and guiding patient outcomes, with rare major complications.
Area of Science:
- Radiology
- Pathology
- Oncology
Background:
- Percutaneous Needle Biopsy (PNB) is a minimally invasive diagnostic procedure.
- It involves inserting a needle into lesions or organs to collect cellular or tissue samples.
- Radiologists guide PNB using various imaging modalities like ultrasound, CT, MRI, and PET-CT.
Purpose of the Study:
- To describe the technique, indications, and applications of Percutaneous Needle Biopsy.
- To highlight the importance of PNB in characterizing lesions and guiding patient management.
- To emphasize the safety and utility of PNB, particularly for retroperitoneal lesions.
Main Methods:
- PNB encompasses fine-needle aspiration biopsy (FNAB) for cytology and core needle biopsy (CNB) for histology.
- The choice of imaging guidance depends on lesion characteristics and patient factors.
- Biopsy samples are used for diagnosing lesion nature, tumor staging, and molecular analyses.
Main Results:
- PNB is crucial for characterizing lesion nature (benign/malignant) and aiding in tumor diagnosis and staging.
- Successful PNB yields sufficient material for accurate diagnosis and informs patient treatment strategies.
- Major complications associated with PNB are infrequent.
Conclusions:
- PNB is an effective and safe technique for obtaining tissue for diagnosis and molecular analysis.
- It plays a vital role in the management of various lesions, including retroperitoneal masses.
- The procedure's success is defined by the procurement of adequate diagnostic material, leading to improved patient outcomes.
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