Related Experiment Video

Updated: Jan 25, 2026

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo
05:14

A Doxorubicin-Induced Murine Model of Dilated Cardiomyopathy In Vivo

Published on: May 16, 2020

5.3K

[Epidemioclinical and evolutionary profile of dilated cardiomyopathies at the University Hospital in Brazzaville,

Stéphane Méo Ikama1,2, Bijou Moualengue1, Jospin Makani1

  • 1Service de Cardiologie et Médecine Interne, Centre Hospitalier Universitaire de Brazzaville, Congo.

The Pan African Medical Journal
|May 16, 2019
PubMed

Insights

Dilated cardiomyopathies (DCMs) are a frequent cause of heart failure in Brazzaville. Treatment protocols include diuretics and ACE inhibitors, but high loss to follow-up limits survival assessment.

Area of Science:

  • Cardiology
  • Internal Medicine

Background:

  • Dilated cardiomyopathies (DCMs) are a significant cause of heart failure (HF).
  • Understanding DCM prevalence and treatment patterns in Brazzaville is crucial for improving patient care.

Observation:

  • A prospective study in Brazzaville included 100 hospitalized HF patients with DCM.
  • The cohort comprised 62% women, with an average age of 52.9 years.
  • Common ECG findings included left ventricular hypertrophy (40%) and normal sinus rhythm (95%).

Findings:

  • Mean left ventricular ejection fraction was 33.4%, with a left ventricle end-diastolic diameter of 65.5 mm.
  • Standard HF treatments were administered: 100% received loop diuretics and ACE inhibitors/ARBs.
  • Beta-blockers were used in 38% of patients.

Implications:

  • DCM is a leading cause of heart failure in Brazzaville.
  • High loss to follow-up (41%) and a short follow-up period hinder survival rate assessment.
  • Further research with longer follow-up is needed to evaluate long-term outcomes and refine treatment protocols.

Keywords:
CongoDilated cardiomyopathiesfrequencyprognosis

More Related Videos

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine10:08

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

Published on: February 17, 2018

13.9K
Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model06:22

Modeling and Evaluation of Murine Diabetic Cardiomyopathy Model

Published on: November 29, 2024

1.4K

Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
509
What is Evolutionary History?02:35

What is Evolutionary History?

Scientists record evolutionary history by analyzing fossil, morphological, and genetic data. The fossil record documents the history of life on Earth and provides evidence for evolution. However, both fossil and living organisms offer evidence that outlines Earth’s evolutionary history.
43.0K
Hospitals-II00:59

Hospitals-II

Hospitals provide inpatient and outpatient services. Inpatient services provide care to patients that stay in the hospital for an extended period, ranging from days to months. Examples of inpatient services include intensive care units, hospital wards, or surgeries. Outpatient services provide care to patients who come to a hospital for a diagnostic or treatment but do not stay overnight —for example, diagnostic tests, surgical procedures, or health education.
Nurses that work in...
1.2K
Hospitals-I01:28

Hospitals-I

Hospitals offer medical and surgical care to the sick and injured, along with accommodation while they recover. At the same time, they also provide outpatient, emergency, psychiatric, and rehabilitation services to meet various community needs. In addition to providing medical care, hospitals also act as hubs for medical research and training. Hospitals use clinical procedures and evidence-based practice standards to deliver patient care. To deliver safe and efficient care, a nurse must stay up...
1.6K
Evolutionary Psychology01:20

Evolutionary Psychology

Evolutionary psychology explores the origins of human behavior and mental processes by framing them within the context of natural selection, a theory famously propounded by Charles Darwin. This field asserts that many behaviors common across human societies — ranging from instinctive fear reactions to complex social interactions — arose as evolutionary adaptations. These adaptations enhanced the survival and reproductive success of our ancestors, thereby becoming embedded in the...
969
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
451