Global epidemiology of prediabetes - present and future perspectives

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Ulrike Hostalek1

  • 1Global Medical Affairs, Merck KGaA, Frankfurterstr. 250, 64293 Darmstadt, Germany.

Clinical Diabetes and Endocrinology
|May 16, 2019
PubMed

Insights

Prediabetes, a state of high blood sugar, indicates a significant risk for developing type 2 diabetes. Understanding its varying diagnostic criteria is key to global prevention efforts.

Area of Science:

  • Endocrinology
  • Metabolic Health
  • Public Health

Background:

  • Prediabetes is an intermediate hyperglycaemic state preceding type 2 diabetes.
  • Individuals with prediabetes face elevated risks of developing diabetes and related complications.
  • Early identification and intervention are crucial for mitigating diabetes progression.

Purpose of the Study:

  • To compare and contrast diagnostic criteria for prediabetes screening.
  • To analyze the impact of different glycaemic measures on prevalence estimates.
  • To discuss global trends in prediabetes prevalence.

Main Methods:

  • Review of existing literature on prediabetes definitions and screening guidelines.
  • Comparative analysis of diagnostic criteria across various organizations.
  • Examination of glycaemic measurement methodologies and their effect on prevalence data.

Main Results:

  • Significant variations exist in prediabetes definitions and screening criteria among different health organizations.
  • Glycaemic measures and diagnostic thresholds substantially influence prevalence estimates.
  • Global prediabetes prevalence is rapidly increasing across all regions.

Conclusions:

  • Harmonizing diagnostic criteria is essential for accurate global prevalence assessment.
  • Standardized screening approaches can facilitate earlier interventions.
  • Addressing the rising global prevalence of prediabetes requires coordinated public health strategies.

Keywords:
DiabetesGlobal burdenPrediabetesPrevalenceScreening tools

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