Related Experiment Video
Updated: Jan 25, 2026

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis
Published on: November 8, 2024
Has the Relationship Between Alcohol Consumption and Alcohol-Related Risky Behaviour Changed in Australia? An
Yvette Mojica-Perez1, Sarah Callinan1, Michael Livingston1,2
1Centre for Alcohol Policy Research, La Trobe University, Australia.
Aims:
Recent studies have pointed to diverging trends between alcohol consumption and harm rates. One explanation for these trends is the normalization hypothesis, which suggests that declines in alcohol consumption will result in more risky behaviour by the remaining drinkers as consumption becomes a more deviant behaviour. We examine how the relationship between alcohol consumption and risky behaviour has changed in Australia over a fourteen-year period.
Methods:
Risky behaviour and alcohol consumption were obtained from six waves (2001, 2004, 2007, 2010, 2013, 2016) of the National Drug Strategy Household Survey (NDSHS). 115,115 respondents aged over 14 were included in this study. Poisson regression analyses were conducted to examine the relationship between risky behaviour and two measures of alcohol consumption (average volume per day and risky drinking occasions per month) over six NDSHS waves. Interaction terms between year and the drinking variables were included in each model to identify shifts in this relationship between consumption and harm.
Results:
Respondents with greater alcohol consumption were more likely to report risky behaviour (IRR = 1.15, 95% CI = 1.13-1.16). Risky behaviour generally declined over time however older participants reported more risky behaviour over time. Generally, the relationship between alcohol consumption and risky behaviour has remained stable, with some very minor upward shifts for young drinkers (aged 14-29; highest IRR = 1.03, 95% CI = 1.01-1.04).
Conclusions:
We found little support for the normalization hypothesis-risky behaviour tends to shift consistently along with drinking levels. Results suggest that recent reductions in alcohol consumption should lead to reductions in rates of harm.
More Related Videos
Related Concept Videos
Oxidation of Alcohols
The process of oxidation in a chemical reaction is observed in any of the three forms:
Ethers from Alcohols: Alcohol Dehydration and Williamson Ether Synthesis
Ethers can be prepared from organic compounds by various methods. Some of them are discussed below,
Preparation of Ethers by Alcohol Dehydration
In this method, in the presence of protic acids, alcohol dehydrates to produce alkenes and ethers under different conditions. For example, in the presence of sulphuric acid, dehydration of ethanol at 413 K yields ethoxyethane, whereas it yields ethene at 443 K.
Protection of Alcohols
Protection
It defines a protecting group as the masking agent to make the more reactive species inert to a given set of conditions. This concept is depicted via the illustration of liquid flow through different outlets in an assembly of pipes. The analogy helps to understand the role...
Preparation of Alcohols via Substitution Reactions
Alcohols can be synthesized from alkyl halides via nucleophilic substitution reactions. The highly polar carbon-halogen bond in the substrate makes halide a good leaving group. The hydroxide ion or water can act as a nucleophile to take the place of halide and form an alcohol. The substitution reactions occur via two different reaction pathways, SN1 or SN2, depending on the nature of carbon attached to the halide.
Primary alcohols are synthesized from primary alkyl halides, and the...
Esters to Alcohols: Hydride Reductions
Lithium aluminum hydride is a source of hydride ions and functions as a nucleophile. The mechanism proceeds in three steps. Firstly, the nucleophilic hydride ion attacks the carbonyl carbon of the ester to form a tetrahedral intermediate. Subsequently, the carbonyl group re-forms,...
Esters to Alcohols: Grignard Reaction
The reaction requires two equivalents of the Grignard reagent and introduces two identical alkyl groups, derived from the Grignard reagent, bonded to the hydroxyl-bearing carbon of the alcohol.
The reaction follows the typical nucleophilic acyl substitution mechanism. The Grignard...

