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Molecular and Cellular Characterization of SIRT1 Allosteric Activators

Michael B Schultz1, Conrad Rinaldi1, Yuancheng Lu1

  • 1Department of Genetics, Blavatnik Institute, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA.

Methods in Molecular Biology (Clifton, N.J.)
|May 16, 2019
PubMed

Keywords:
ADP-riboseAgingAllosteric activatorDeacetylaseDeacylaseEpigeneticsHistoneHistone deacetylase (HDAC)LongevityMembrane potentialMetabolismMitochondriaNAD+NicotinamideReactive oxygen species (ROS)Recombinant proteinResveratrolSIRT1SirtuinSirtuin-activating compound (STAC)p53

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