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Updated: Jan 24, 2026

Composite Scaffolds of Interfacial Polyelectrolyte Fibers for Temporally Controlled Release of Biomolecules
Published on: August 19, 2015
A MOF@COF Composite with Enhanced Uptake through Interfacial Pore Generation
Luis Garzón-Tovar1, Javier Pérez-Carvajal1, Amirali Yazdi1
1Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and BIST, Campus UAB, Bellaterra, 08193, Barcelona, Spain.
Abstract:
Herein, we describe a new class of porous composites comprising metal-organic framework (MOF) crystals confined in single spherical matrices made of packed covalent-organic framework (COF) nanocrystals. These MOF@COF composites are synthesized through a two-step method of spray-drying and subsequent amorphous (imine-based polymer)-to-crystalline (imine-based COF) transformation. This transformation around the MOF crystals generates micro- and mesopores at the MOF/COF interface that provide far superior porosity compared to that of the constituent MOF and COF components added together. We report that water sorption in these new pores occurs within the same pressure window as in the COF pores. Our new MOF@COF composites, with their additional pores at the MOF/COF interface, should have implications for the development of new composites.
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