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Carrying rates of epinephrine devices in children with food-induced anaphylaxis
Chanonart Ratanaprug1, Witchaya Srisuwatchari1, Orathai Jirapongsananuruk1
1Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Insights
Most children with food-induced anaphylaxis carry epinephrine auto-injectors. However, less than half use them during reactions, often due to fear of injections. Training is crucial.
Area of Science:
- Pediatric Allergy and Immunology
- Emergency Medicine
- Public Health
Background:
- Anaphylaxis requires prompt epinephrine administration for life-saving treatment.
- Epinephrine auto-injector features may affect patient willingness to carry.
- Carrying rates of epinephrine auto-injectors are unknown in children with a history of food-induced anaphylaxis.
Purpose of the Study:
- To determine the prevalence of epinephrine auto-injector carrying in children with a history of food-induced anaphylaxis.
- To identify factors influencing the decision to carry and use epinephrine auto-injectors.
Main Methods:
- A cross-sectional study involving structured interviews with primary caregivers of children with a history of food-induced anaphylaxis.
- Data collected on epinephrine carrying habits, reasons for non-carrying, school first-aid availability, and reasons for epinephrine non-use.
Main Results:
- Epinephrine auto-injectors were carried by 84.7% of children (57.6% always, 27.2% sometimes).
- Primary reasons for not carrying included belief in allergen avoidance and lack of school first-aid facilities (48.3% availability).
- Of those with relapsing episodes, 82.9% carried epinephrine, but only 58.8% used it, with fear of injection being a common barrier (28.5%).
Conclusions:
- The majority of children with food-induced anaphylaxis carry epinephrine auto--injectors.
- Despite carrying, epinephrine auto-injector use during anaphylactic episodes remains suboptimal, with fear of injection being a significant factor.
- Interventions to enhance epinephrine auto-injector carrying and provide injection training are essential.
Background:
Carrying epinephrine can save lives in patients with anaphylaxis. The feature of epinephrine in prefilled syringe that commonly prescribed in Thailand may influence the willingness to carry. However, the rates of carrying prefilled syringe epinephrine are unknown in children with history of food-induced anaphylaxis.
Objective:
To determine the rate of epinephrine carrying in children with history of food-induced anaphylaxis and factors influencing the decision to use the devices.
Methods:
A cross-sectional study was conducted by performing the structured interview in the parent(s) who were the main caregiver of the children with history of food-induced anaphylaxis.
Results:
The parents of 99 children (male, 50.5%) were interviewed. The median age of the child was 11 years old (range, 9 months to 18 years). Rate of carrying epinephrine was 84.7% (always 57.6%, some occasions 27.2%). The most common reason for not carrying was the thoughts that the children could avoid the food allergens. The first-aid facility at school was available in 48.3%. Rate of carrying epinephrine tended to be lesser in children attend the schools without first aid facility (p = 0.053). Forty-one patients had relapsing episodes, 34 (82.9%) had epinephrine carried, and 20 (58.8%) injected the epinephrine. The most common reason for not using epinephrine despite carrying was that they were afraid of getting injection (28.5%).
Conclusion:
Most children with history of food-induced anaphylaxis carried epinephrine, but only half used it at the episodes. Interventions to promote epinephrine-carrying and injection training are needed in our setting.
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