Related Experiment Video
Updated: Jan 24, 2026

Determining The Electromyographic Fatigue Threshold Following a Single Visit Exercise Test
Published on: July 27, 2015
Disability as a determinant of fatigue in MS patients
Fernanda M Taveira1, Nayara F T Braz1,2, Elizabeth R Comini-Frota1
1Universidade Federal de Minas Gerais, Programa de Pós-graduação em Neurociências, Belo Horizonte MG, Brasil.
Introduction:
Fatigue is one of the most frequent and disabling symptoms in multiple sclerosis (MS). Central, psychological, and peripheral factors may contribute to the occurrence of fatigue.
Objectives:
The current study aimed to evaluate potential fatigue determinants in patients with relapsing-remitting MS with a low functional impairment.
Methods:
We compared inflammatory markers, respiratory pressures, disability, and quality of life in 39 relapsing-remitting MS patients with and without fatigue.
Results:
Patients with relapsing-remitting MS with fatigue had higher Expanded Disability Status Scale scores (p = 0.002). We observed a significant association between the results of the Guy Neurological Disability Scale, the Functional Assessment of MS Quality of Life Rating Scale and the presence of fatigue (p < 0.05).
Conclusions:
The degree of functional impairment is a determinant for the presence of fatigue in MS patients, but respiratory function and inflammatory markers are not.
Related Concept Videos
Intellectual Disability
Learning Disabilities
Dyslexia
Dyslexia is a...
Fatigue
Muscle Recovery and Fatigue
Fatigue Strength of Concrete
Determining Order of Reaction

