Centralization of the IARC Biobank: Combining Multiple Sample Collections into a Common Platform

Area of Science:

• Oncology
• Biobanking
• Epidemiology

Background:

• The International Agency for Research on Cancer (IARC), part of the World Health Organization (WHO), conducts global cancer research.
• IARC's Biobank supports worldwide studies with sample collections and preanalytical services.
• Historically, IARC sample collections were managed in disparate, project-specific databases.

Purpose of the Study:

• To centralize IARC's multiple sample collections into a unified platform.
• To establish a common biobank database and an up-to-date inventory of biological resources.
• To implement a governance structure for transparent resource sharing.

Main Methods:

• Initiated a program in 2010 to centralize sample collections.
• Adopted a common database with a minimum dataset for incoming samples.
• Performed data file checking, sample storage verification, data harmonization, and data migration.
• Established a Biobank Steering Committee and an access policy.

Main Results:

• Created a common biobank database.
• Developed an up-to-date inventory of IARC's biological resources.
• Established a governance structure to guide resource sharing.

Conclusions:

• Centralization of biobank samples enhances resource management and accessibility.
• A unified database and governance structure facilitate transparent sharing of cancer research resources.
• The initiative supports IARC's mission in global cancer research and prevention.