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Published on: May 21, 2017
Non-infectious aortic and mitral valve vegetations in a patient with eosinophilic granulomatosis with polyangiitis
Kamalesh Karthikeyan1, Sudarshan Balla2, Martin A Alpert3
1University of Missouri-Columbia, Columbia, Missouri, USA.
Abstract:
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare form of vasculitis characterised by atopic manifestations, inflammation of small-sized to medium-sized arteries and veins, hypereosinophilia and tissue infiltration with eosinophils. Cardiac complications occur most commonly in the absence of antineutrophil cytoplasmic antibodies. Cardiac complications include coronary arteritis (rare), pericarditis, myocarditis, endocardial fibrosis (Loeffler's endocarditis) and intracavitary thrombosis of the left or right ventricle. This is the first reported case of large non-infectious valvular vegetations associated with EGPA.
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