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Neuronavigation and Laparoscopy Guided Ventriculoperitoneal Shunt Insertion for the Treatment of Hydrocephalus
Published on: October 14, 2022
Ventriculoperitoneal Shunt Infection Caused by Enterococcus gallinarum in a Pediatric Patient: A Case Report
1Department of Pharmacy, Florida Hospital Orlando, Orlando, Florida, United States.
Insights
Enterococcus gallinarum, a bacterium with natural vancomycin resistance, can cause ventriculoperitoneal shunt infections in children. Prompt antibiotic treatment led to a full recovery in a pediatric case.
Area of Science:
- Microbiology
- Infectious Diseases
- Pediatrics
Background:
- Enterococcus gallinarum is a Gram-positive bacterium commonly found in the gut.
- This species exhibits intrinsic resistance to vancomycin, a critical antibiotic.
- Ventriculoperitoneal (VP) shunts are used to treat hydrocephalus in children.
Observation:
- A 4-year-old female patient developed a VP shunt infection.
- Cerebrospinal fluid (CSF) cultures identified Enterococcus gallinarum as the causative agent.
- The infection presented as a complication of VP shunt placement.
Findings:
- The patient was treated with ampicillin and gentamicin, demonstrating synergistic activity.
- A 16-day antibiotic course resulted in negative CSF and blood cultures.
- Complete clinical cure of the ventriculoperitoneal shunt infection was achieved.
Implications:
- This case highlights the importance of recognizing vancomycin-resistant Enterococcus species in clinical practice.
- Prompt and appropriate antibiotic therapy is crucial for managing shunt infections.
- Increased awareness of Enterococcus gallinarum's resistance patterns is necessary for effective pediatric infectious disease management.
Abstract:
Enterococcus gallinarum is a common colonizer of the gastrointestinal tract that expresses intrinsic vancomycin resistance. This case report describes an E. gallinarum ventriculoperitoneal (VP) shunt infection in a pediatric patient. A 4-year-old female patient presented with cerebrospinal fluid (CSF) cultures from a VP shunt significant for E. gallinarum . The patient received ampicillin and synergistic gentamicin. She completed a total of 16 days of therapy following 2 weeks of negative CSF and blood cultures with full clinical cure of infection. The patient was successfully treated following a 2-week course of antibiotics. Awareness of Enterococcus species with intrinsic vancomycin resistance should be increased.
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