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High-resolution anal manometry: Repeatability, validation, and comparison with conventional manometry.

Jonathan Gosling1, Andrew Plumb1, Stuart A Taylor1

  • 1Department of Specialist X-Ray, University College London Hospitals NHS Foundation Trust, London, UK.

Neurogastroenterology and Motility
|May 17, 2019
PubMed
Summary
This summary is machine-generated.

High-resolution anorectal manometry (HRAM) is a validated technique for measuring anal sphincter function, showing precision comparable to conventional manometry (CM). New normal values are needed due to measurement differences.

Keywords:
anorectal manometryfecal incontinencepelvic floor dysfunctiontest validation

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Area of Science:

  • Gastroenterology and Colorectal Surgery
  • Pelvic Floor Disorders Diagnostics

Background:

  • Accurate anal sphincter function measurement is crucial for treating common pelvic floor disorders.
  • Existing diagnostic methods require validation for precise functional assessment.

Purpose of the Study:

  • To establish the repeatability and validate high-resolution anorectal manometry (HRAM).
  • To compare HRAM performance against conventional manometry (CM).
  • To generate definitive normal range data for HRAM.

Main Methods:

  • A test-retest repeatability study was conducted on 80 healthy volunteers.
  • A 16-channel water-perfused HRAM catheter was compared with an 8-channel CM catheter.
  • The station pull-through technique was employed for data acquisition.

Main Results:

  • HRAM demonstrated similar precision to CM for resting pressure (ICC 0.73 vs 0.68) and squeeze increment (ICC 0.90 vs 0.94).
  • HRAM recorded 10% lower resting pressures compared to CM.
  • HRAM measured 27% higher squeeze pressures than CM.

Conclusions:

  • High-resolution anorectal manometry is a valid diagnostic technique.
  • HRAM offers comparable precision to conventional manometry.
  • Significant differences in measurements necessitate the establishment of new normal values for HRAM.