Related Experiment Video

Updated: Jan 24, 2026

Seawater Sampling and Collection
08:23

Seawater Sampling and Collection

Published on: June 17, 2009

20.7K

AmyCo: the amyloidoses collection

Katerina C Nastou1, Georgia I Nasi1, Paraskevi L Tsiolaki1

  • 1a Section of Cell Biology and Biophysics, Department of Biology, School of Sciences, National and Kapodistrian University of Athens , Panepistimiopolis , Athens , Greece.

Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis
|May 17, 2019
PubMed

Insights

Amyloid fibrils, linked to amyloidoses and other diseases, are now cataloged in AmyCo. This new database offers a comprehensive resource for understanding amyloid deposition disorders.

Area of Science:

  • Biochemistry
  • Pathology
  • Bioinformatics

Background:

  • Amyloid fibrils result from protein misfolding and aggregation, leading to amyloidoses and complications in other diseases.
  • The heterogeneity of amyloidoses necessitates better classification and understanding.
  • Amyloid deposition is a hallmark of various pathological conditions, including neurodegenerative and endocrine diseases.

Purpose of the Study:

  • To introduce AmyCo, a freely accessible database of diseases associated with amyloid deposition.
  • To classify 75 diseases into distinct categories: amyloidosis and clinical conditions with amyloidosis.
  • To provide a centralized, up-to-date repository for amyloid-related disorder information.

Main Methods:

  • Development of a comprehensive collection of amyloidoses and related clinical disorders.
  • Classification of diseases based on amyloid deposition.
  • Annotation of database entries with causative proteins, deposit components, and affected tissues.
  • Cross-referencing with established databases like ICD-10, MeSH, OMIM, PubMed, AmyPro, and UniProtKB.

Main Results:

  • AmyCo classifies 75 diseases related to amyloid deposition.
  • Each entry details the major protein component, other deposit constituents, and affected organs.
  • Database entries are extensively annotated and linked to multiple external resources.

Conclusions:

  • AmyCo represents the first comprehensive and up-to-date repository for amyloidoses and associated diseases.
  • The database facilitates research and understanding of amyloid deposition disorders.
  • The AmyCo web interface is publicly available for access and utilization.
Keywords:
Amyloidaggregationamyloid depositsamyloidosisdatabase

More Related Videos

Blood Collection Through Subclavian Vein Puncture in Mice06:03

Blood Collection Through Subclavian Vein Puncture in Mice

Published on: May 4, 2019

37.8K
Collection and Extraction of Saliva DNA for Next Generation Sequencing06:58

Collection and Extraction of Saliva DNA for Next Generation Sequencing

Published on: August 27, 2014

40.0K

Related Concept Videos

Data Collection II01:29

Data Collection II

The nursing history captures and records the patient's health status, so that a care plan evolves to meet the patient's individual needs. The nursing health history is a part of the initial assessment. A comprehensive history covers all health dimensions and plays a significant role in the assessment process. A comprehensive history includes the patient's biographical information, reasons for seeking health care, expectations, present and past health history, medications, and...
9.6K
Data Collection I01:30

Data Collection I

Data collection gathers information needed to make accurate judgments about a patient's present condition. During a health history interview, subjective data is collected from the patient, their caregivers, or family members, and objective data is collected through observations and physical assessment. Patients are the primary source of subjective data. Thus information gathered from patients through interviews, observations, and physical examination is primary data. Secondary sources of...
7.9K
Data Collection by Experiments01:13

Data Collection by Experiments

Data collection is a systematic method of obtaining, observing, measuring, and analyzing accurate information. An experimental study is a standard method of data collection that involves the manipulation of the samples by applying some form of treatment prior to data collection. It refers to manipulating one variable to determine its changes on another variable. The sample subjected to treatment is known as “experimental units.”
An example of the experimental method is a public...
27.2K
Data Collection by Survey01:07

Data Collection by Survey

The systematic method of obtaining and analyzing accurate information of a population is called data collection. A survey is a standard method of data collection that involves collecting information from a target human population about their experience, opinion, or knowledge of a product, service, or process. The responses are recorded and interpreted. The most common survey examples are written questionnaires, face-to-face or telephonic conversations, focus groups, and electronic (e-mail or...
8.8K
Data Collection III01:05

Data Collection III

The physical assessment examines the patient for objective data that defines the patient's condition, and aids in formulating the nursing care plan. The purpose of physical assessment is a health status appraisal, which includes identifying health problems, and establishing a database for nursing intervention.
The principles to begin the physical assessment include conducting a comprehensive or problem-related history in a quiet, well-lit room, emphasizing privacy and comfort for the...
4.0K
Data Collection by Observations01:08

Data Collection by Observations

Data collection refers to a systematic way of obtaining, observing, measuring, and analyzing accurate information. Observational studies are one of the most widely used methods of data collection. It involves collecting data by observing the behavior and physical characteristics of a sample without making any modifications to the sample.
An astronomer viewing the motion and brightness of stars in the sky and recording the data is an example of observational data collection. A botanist recording...
14.7K