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Updated: Jan 24, 2026

Dual-mode Imaging of Cutaneous Tissue Oxygenation and Vascular Function
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Plasmacytic cutaneous pathology: A review.

Noreen M Walsh1,2,3, Heinz Kutzner4, Luis Requena5

  • 1Department of Pathology, Queen Elizabeth II Health Sciences Center, Nova Scotia Health Authority (Central Zone), Halifax, Canada.

Journal of Cutaneous Pathology
|May 17, 2019
PubMed
Summary
This summary is machine-generated.

This review covers skin conditions linked to plasma cell disorders, including B-lymphocyte related proliferations. It details diagnostic features to improve accuracy in identifying these plasmacytic and lymphoplasmacytic skin diseases.

Keywords:
amyloidimmunoglobulinslymphomamyelomaplasma cell

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Area of Science:

  • Dermatology
  • Hematology
  • Pathology

Background:

  • Plasma cells, derived from B-lymphocytes, can cause various skin disorders.
  • These disorders range from inflammatory conditions to neoplastic proliferations.
  • Cutaneous involvement can occur in primary skin lesions or as part of multisystem diseases.

Purpose of the Study:

  • To review the spectrum of cutaneous disorders associated with plasmacytic and lymphoplasmacytic pathology.
  • To highlight key clinical and pathological features for improved diagnostic accuracy.
  • To discuss recent advances in understanding these skin conditions.

Main Methods:

  • Histopathological classification of cutaneous disorders.
  • Review of conditions with plasma cell infiltrates, plasma cell product deposits, and miscellaneous complications.
  • Inclusion of both primary cutaneous lesions and systemic disease involvement.

Main Results:

  • The spectrum includes tumefactive and circulatory manifestations.
  • Conditions are categorized based on plasma cell infiltrates, product deposits, or complications.
  • Key clinical and pathological features are presented for each entity.

Conclusions:

  • Accurate diagnosis relies on understanding dermatopathological characteristics.
  • This review aims to enhance diagnostic accuracy for practitioners.
  • Knowledge of these disorders is crucial for effective patient management.