Related Experiment Video
Updated: Jan 24, 2026

Formation of Dispersible Taohong Siwu Tablets
Published on: February 3, 2023
Influence of the Punch Speed on the Die Wall/Powder Kinematic Friction During Tableting
Léo Desbois1, Pierre Tchoreloff1, Vincent Mazel1
1University Bordeaux, CNRS, I2M Bordeaux, 146, rue Léo Saignat, 33000 Bordeaux, France.
Abstract:
Influence of the compaction speed on the final tablet properties is an important challenge during the scale-up of a solid dosage form. This strain rate sensitivity is generally attributed to the time dependent deformation behavior of the powder. In this work, we studied the influence of the speed on another important factor during compaction: friction between the tablet/powder and the die. An original experimental methodology was developed to study the evolution of the kinematic friction coefficient between the tablet and the die as a function of the sliding speed of the tablet on the die wall. This methodology made it possible to separate the speed used to make the tablet from the speed used to measure the friction coefficient. Results indicate that the kinematic coefficient of friction increases with the sliding speed following a logarithmic trend. This trend was observed for 4 different pharmaceutical excipients. Moreover, it was proved that the speed dependency is an intrinsic property of the friction between a tablet and a die lubricated using magnesium stearate.
Related Concept Videos
Kubler Ross's Stages of Dying
In denial, individuals reject the reality of their condition, often thinking, "This isn't true; I feel fine," as a way to protect themselves from...
Kinetic Friction
Types of Friction Problems
The first type of dry friction problem involves situations where there is no apparent impending motion....
Friction: Problem Solving
Initially, a visual representation of the...
Kinematic Equations - I
Characteristics of Dry Friction
Before the wheelbarrow starts moving, the static frictional force acts tangentially to the contact surface, opposing the force that is about to induce the motion. This frictional force prevents the...

