Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease-I: Introduction

Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.

Chronic Obstructive Pulmonary Disease-V: Management

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Chronic Obstructive Pulmonary Disease-V: Nursing Management

Nursing management of Chronic Obstructive Pulmonary Disease (COPD) is crucial for providing thorough care and support to patients. Nurses play an integral role in this process through detailed assessment, careful planning, targeted interventions, and ongoing evaluation. Here's an overview of the critical steps in nursing management for COPD.
Assessment

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The clinical and chest radiographic features of respiratory syncytial virus-associated severe respiratory illness in hospitalised adults in South Africa, 2022 - 2023.

African journal of thoracic and critical care medicine·2026

Same author

Proceedings from the Third International Post-Tuberculosis Symposium: expanding the circle.

IJTLD open·2025

Same author

The utility of a smartphone electronic referral application in facilitating telemedicine in pulmonology.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2025

Same author

South African Thoracic Society consensus statement on transbronchial lung cryobiopsy for interstitial lung disease.

African journal of thoracic and critical care medicine·2025

Same author

Non-tuberculous mycobacterial disease in a high TB/HIV burden setting.

IJTLD open·2025

Same author

The utility of transbronchial cryobiopsy performed under conscious sedation for interstitial lung diseases in a resource constrained setting.

African journal of thoracic and critical care medicine·2025

Same journal

Rifamycin-based regimens for preventive treatment in low TB incidence countries.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2026

Same journal

The Kochi Declaration 2024 - A catalyst for global TB elimination through private sector engagement.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2026

Same journal

Preventing lung function decline and pleural thickening after pleural TB: a systematic review.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2026

Same journal

Aircraft contact investigations for TB on domestic and inbound flights to the United States.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2026

Same journal

Treatment outcome of extracorporeal membrane oxygenation in critically ill patients with pulmonary TB.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2026

Same journal

Factors associated with sputum culture positivity of <i>Mycobacterium tuberculosis</i>.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 24, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

Histologically confirmed tuberculosis-associated obstructive pulmonary disease.

B W Allwood¹, J Rigby², S Griffith-Richards³

¹Division of Pulmonology, Department of Medicine, Stellenbosch University & Tygerberg Academic Hospital, Cape Town.

The International Journal of Tuberculosis and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease

|May 18, 2019

Summary

This summary is machine-generated.

Tuberculosis (TB) can cause chronic airflow limitation (CAL), a condition potentially distinct from COPD. This case study details a young man with severe CAL due to residual TB lung pathology.

More Related Videos

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Published on: May 10, 2024

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

Related Experiment Videos

Last Updated: Jan 24, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure

Published on: August 25, 2017

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Author Spotlight: Efficacy of Auricular Pressure Bean Therapy in Reducing Wheezing Symptoms

Published on: May 10, 2024

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

Area of Science:

Pulmonology
Pathology
Infectious Disease

Background:

Chronic airflow limitation (CAL) is a known long-term consequence of tuberculosis (TB).
The specific disease processes underlying TB-associated obstructive pulmonary disease (TOPD) remain poorly understood.
Existing research often links CAL to smoking-related chronic obstructive pulmonary disease (COPD) or bronchiectasis.

Observation:

A 23-year-old non-smoking male presented with severe CAL following a single episode of TB.
No other risk factors for CAL were identified in the patient.
Lung biopsies were performed to investigate the cause of the severe airflow limitation.

Findings:

Histological examination confirmed residual post-tuberculosis pathology.
The pathology affected small airways and pulmonary vessels throughout the lung.
This detailed pathological description in the small airways and vessels is a novel finding.

Implications:

These findings suggest that TB-associated obstructive pulmonary disease (TOPD) may represent a distinct phenotype of CAL.
TOPD could be differentiated from smoking-related COPD and bronchiectasis based on its underlying pathology.
Further research into TOPD is warranted to understand its distinct characteristics and management.