Related Experiment Video
Updated: Jan 24, 2026
04:19
A Mouse Model of Single and Repetitive Mild Traumatic Brain Injury
Published on: June 20, 2017
11.7K
Extraskeletal Osteosarcoma Recognized following Acute Traumatic Injury
Karleigh R Curfman1, Shawna L Morrissey1
1Conemaugh Memorial Medical Center, Department of General Surgery, Johnstown, Pennsylvania, USA.
Case Reports in Oncology
|May 18, 2019
Summary
Extraskeletal osteosarcoma (ESOS) is a rare soft tissue sarcoma. Trauma symptoms like swelling can mask ESOS, delaying diagnosis and treatment.
Area of Science:
- Oncology
- Orthopedic Oncology
- Soft Tissue Pathology
Background:
- Extraskeletal osteosarcoma (ESOS) is a rare malignant tumor, comprising less than 2% of all soft tissue sarcomas.
- Identified risk factors include advanced age, prior radiation exposure, and a debated association with trauma.
- Clinical presentation often involves localized tenderness and swelling.
Observation:
- In trauma patients, ESOS symptoms can be mistaken for typical traumatic injuries such as hematomas.
- This diagnostic challenge can lead to significant delays in identifying the underlying extraskeletal osteosarcoma.
Findings:
- The subtle presentation of ESOS, particularly when superimposed on trauma, complicates early detection.
- Misinterpretation of symptoms as purely traumatic hinders timely referral and definitive diagnosis.
Implications:
- Delayed diagnosis of ESOS can negatively impact patient prognosis and treatment outcomes.
- Increased awareness among clinicians is crucial for prompt recognition and management of this rare sarcoma.
- Further research into the trauma association may clarify diagnostic pathways for extraskeletal osteosarcoma.
Related Concept Videos
01:22Acute Kidney Injury I: Introduction
639
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
639
01:29Acute Kidney Injury II: Pathophysiology
973
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
973
01:22Acute Kidney Injury VI: Nursing Management
424
Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
424
01:20Acute Kidney Injury V: Interprofessional Care
312
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
312
01:29Acute Kidney Injury III: Clinical Manifestations
857
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
857
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
286
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
286