Related Experiment Video
Updated: Jan 24, 2026
08:43
Molten-Salt Synthesis of Complex Metal Oxide Nanoparticles
Published on: October 27, 2018
18.8K
Phytosynthesized metal oxide nanoparticles for pharmaceutical applications
Swetha Andra1, Satheesh Kumar Balu2, Jaison Jeevanandham3
1Department of Textile Technology, Anna University, Chennai, Tamil Nadu, 600025, India.
Naunyn-Schmiedeberg'S Archives of Pharmacology
|May 18, 2019
Summary
Green synthesis of metal oxide nanoparticles using plant extracts offers a cost-effective and eco-friendly alternative to traditional methods. Phytosynthesized nanoparticles show reduced toxicity, paving the way for pharmaceutical applications.
Area of Science:
- Nanotechnology
- Green Chemistry
- Materials Science
Background:
- Metal oxide nanoparticles have diverse applications but traditional synthesis methods are costly and involve toxic chemicals.
- Green chemistry approaches are being explored for nanoparticle synthesis to mitigate environmental and health risks.
- Plant-mediated synthesis (phytosynthesis) is a promising green method due to readily available plant sources and reduced toxicity.
Purpose of the Study:
- To provide an overview of recent advancements in the phytosynthesis of metal oxide nanoparticles.
- To discuss the toxicological analysis of phytosynthesized metal oxide nanoparticles in various models.
- To explore the mechanisms, pharmaceutical applications, and therapeutic potential of these nanoparticles.
Main Methods:
- Literature review of recent research on phytosynthesis of metal oxide nanoparticles.
- Analysis of studies reporting toxicological assessments in cell lines and animal models.
- Examination of research on the mechanisms of action and therapeutic efficacy.
Main Results:
- Phytosynthesis utilizes plant secondary metabolites (flavonoids, terpenoids, saponins) for nanoparticle formation and stabilization.
- Phytosynthesized metal oxide nanoparticles exhibit lower toxicity compared to chemically synthesized counterparts.
- These nanoparticles demonstrate potential in pharmaceutical applications and disease treatment.
Conclusions:
- Phytosynthesis is a viable and sustainable method for producing metal oxide nanoparticles with reduced toxicity.
- Further research into the mechanisms and applications of phytosynthesized nanoparticles is warranted for therapeutic development.
- Plant-derived nanoparticles offer a promising avenue for safer and more effective nanomedicine.
Keywords:
CytotoxicityIn vitro analysisMetal oxide nanoparticlesPharmaceutical applicationsPhytochemicalsMore Related Videos
12:19Identification of Metal Oxide Nanoparticles in Histological Samples by Enhanced Darkfield Microscopy and Hyperspectral Mapping
Published on: December 8, 2015
12.9K
14:53In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis
Published on: February 3, 2018
7.6K
Related Concept Videos
03:14Oxidation Numbers
42.3K
In redox reactions, the transfer of electrons occurs between reacting species. Electron transfer is described by a hypothetical number called the oxidation number (or oxidation state). It represents the effective charge of an atom or element, which is assigned using a set of rules.
42.3K
03:06Alkali Metals
24.3K
Group 1 elements are soft and shiny metallic solids. They are malleable, ductile, and good conductors of heat and electricity. The melting points of the alkali metals are unusually low for metals and decrease going down the group, while the density increases going down the group with the exception of potassium (Table 1).
Table 1: Properties of the alkali metals
Table 1: Properties of the alkali metals
24.3K
01:26Pharmaceutical Equivalents
190
As defined by regulatory standards, pharmaceutical equivalents require generic drug products to have identical dosage forms and chemically identical active pharmaceutical ingredients (APIs). They must adhere to compendial or applicable standards for potency, content uniformity, disintegration times, and dissolution rates. In the case of modified-release dosage forms, variations in drug content are permissible as long as the delivered amount remains consistent with the innovator drug product.
190
03:11Oxidation-Reduction Reactions
75.2K
Oxidation–Reduction Reactions
75.2K
02:58Properties of Transition Metals
29.7K
Transition metals are defined as those elements that have partially filled d orbitals. As shown in Figure 1, the d-block elements in groups 3–12 are transition elements. The f-block elements, also called inner transition metals (the lanthanides and actinides), also meet this criterion because the d orbital is partially occupied before the f orbitals.
29.7K
02:51Metal-Ligand Bonds
24.1K
The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
24.1K