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Studies on 1,2,3-triazole derivatives as potential inhibitors of the cyclo-oxygenase
Abstract:
A number of novel alpha-[4-substituted-(1,2,3-triazole)]propionates have been prepared and tested as inhibitors of arachidonic acid-induced malondialdehyde formation in human platelets. The obtained products confirmed previous structure-activity relationships. Some of them showed moderate inhibitory activity.