Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Insufficient Sleep and Sleep Deprivation01:13

Insufficient Sleep and Sleep Deprivation

858
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
858
Energy to Drive Translocation01:37

Energy to Drive Translocation

2.7K
Mitochondrial protein import is powered by two distinct energy sources: ATP hydrolysis and electrochemical potential across the inner membrane. Newly synthesized precursors are bound by cytosolic chaperones of the Hsp70 family, which guide them to the import receptors on the mitochondrial surface. Utilizing the energy of ATP hydrolysis, Hsp70 chaperones transfer these precursors to the TOM receptors on the mitochondrial outer membrane.
Generally, polypeptides are unfolded by two distinct...
2.7K
Stages of Sleep01:22

Stages of Sleep

1.4K
Sleep progresses through distinct stages, each characterized by specific brain wave patterns and physiological responses ranging from wakefulness to stages of non-rapid eye movement, known as non-REM, to rapid eye movement, referred to as REM. Understanding these stages helps in recognizing how sleep supports various bodily and cognitive functions.
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
1.4K
Understanding Sleep01:11

Understanding Sleep

1.4K
Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
1.4K
Sleep Apnea01:21

Sleep Apnea

514
Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
514
M-Cdk Drives Transition Into Mitosis02:15

M-Cdk Drives Transition Into Mitosis

6.4K
Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
Cyclin-dependent kinases, or Cdks, work in concert with cyclins to control cell cycle transitions. M-Cdk, a complex of Cdk1 bound to M cyclin, is a well-known example of this coordinated control that drives the transition from the G2 to the M phase.
M cyclin...
6.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Presynaptic Neurotransmission: A Bottleneck to Recovery From General Anesthesia?

Anesthesia and analgesia·2025
Same author

Wakefulness can be distinguished from general anesthesia and sleep in flies using a massive library of univariate time series analyses.

PLoS biology·2025
Same author

A basic role for glia in sleep homeostasis.

Nature neuroscience·2025
Same author

Long-term multichannel recordings in Drosophila flies reveal altered predictive processing during sleep compared with wake.

The Journal of experimental biology·2025
Same author

Alcohol use: Passing out has long-term effects on sleep.

Current biology : CB·2025
Same author

Synapse-Specific Trapping of SNARE Machinery Proteins in the Anesthetized <i>Drosophila</i> Brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2024

Related Experiment Video

Updated: Jan 24, 2026

Quantitative Measurement of the Immune Response and Sleep in Drosophila
12:16

Quantitative Measurement of the Immune Response and Sleep in Drosophila

Published on: December 4, 2012

15.9K

Visual experience drives sleep need in Drosophila.

Leonie Kirszenblat1, Rebecca Yaun1, Bruno van Swinderen1

  • 1Queensland Brain Institute, The University of Queensland, St Lucia, Australia.

Sleep
|May 18, 2019
PubMed
Summary

Visual experience influences sleep need in fruit flies. Complex, non-repetitive visual stimuli, especially those involving motion circuits, increase sleep pressure in Drosophila.

Area of Science:

  • Neuroscience
  • Behavioral Biology
  • Chronobiology

Background:

  • Sleep is crucial for optimal brain function.
  • Waking experiences can modulate sleep patterns and needs.

Purpose of the Study:

  • To investigate the impact of visual experience on sleep in Drosophila melanogaster.
  • To understand how motion perception and complex visual stimuli influence sleep pressure.

Main Methods:

  • Utilized wild-type and optomotor-blind (omb) mutant Drosophila.
  • Employed optogenetics to activate motion-processing neurons (HS/VS).
  • Exposed flies to repetitive motion stimuli and complex, shuffled movie sequences.

Main Results:

  • Optomotor-blind mutants exhibited significantly reduced and less consolidated sleep.
Keywords:
Drosophilaoptogeneticssleepvisual behaviour

More Related Videos

The Sleep Nullifying Apparatus: A Highly Efficient Method of Sleep Depriving Drosophila
06:06

The Sleep Nullifying Apparatus: A Highly Efficient Method of Sleep Depriving Drosophila

Published on: December 14, 2020

4.2K
Author Spotlight: Deciphering Memory and Learning Through Neural Implants for Multi&#45;Region Brain Studies
08:51

Author Spotlight: Deciphering Memory and Learning Through Neural Implants for Multi-Region Brain Studies

Published on: April 26, 2024

1.9K

Related Experiment Videos

Last Updated: Jan 24, 2026

Quantitative Measurement of the Immune Response and Sleep in Drosophila
12:16

Quantitative Measurement of the Immune Response and Sleep in Drosophila

Published on: December 4, 2012

15.9K
The Sleep Nullifying Apparatus: A Highly Efficient Method of Sleep Depriving Drosophila
06:06

The Sleep Nullifying Apparatus: A Highly Efficient Method of Sleep Depriving Drosophila

Published on: December 14, 2020

4.2K
Author Spotlight: Deciphering Memory and Learning Through Neural Implants for Multi&#45;Region Brain Studies
08:51

Author Spotlight: Deciphering Memory and Learning Through Neural Implants for Multi-Region Brain Studies

Published on: April 26, 2024

1.9K
  • Optogenetic activation of HS/VS neurons increased subsequent sleep.
  • Repetitive motion stimuli did not elevate sleep pressure.
  • Complex, non-repetitive visual sequences enhanced sleep consolidation.
  • Conclusions:

    • Specific visual experiences, particularly those engaging motion circuits and complex imagery, drive sleep need.
    • Motion-processing circuits play a key role in mediating visual influences on sleep.
    • Drosophila visual system complexity correlates with sleep regulation.