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Updated: Jan 24, 2026

Adaptation of Semiautomated Circulating Tumor Cell CTC Assays for Clinical and Preclinical Research Applications
Published on: February 28, 2014
Partners in Crime: Neutrophil-CTC Collusion in Metastasis
Bingqian Guo1, Trudy G Oliver1
1Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA.
Abstract:
A recent study in Nature (Szczerba et al. 2019;566:553-557) reports that the association of neutrophils with circulating tumor cells (CTCs) in the blood of patients with breast cancer can promote CTC proliferation and metastasis. These findings reveal a new mechanism by which the innate immune system may be co-opted to drive tumor progression.
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