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Measures of the efficiency of natural selection during gene substitution
1Department of Biology, University of Rochester, Rochester, NY 14627, USA.
Abstract:
Natural selection is not perfectly efficient: it does not cause the instantaneous substitution of a beneficial mutation. Instead, substitution takes time, reflecting the statistical consequences of fitness differences over some number of generations. In this note, I suggest two measures of the efficiency of natural selection during gene substitution. I compare these measures against both ideal (instantaneous) and failed evolution. I also compare these measures to Haldane's cost of natural selection.
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