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Updated: Jan 24, 2026

Mobile Game-based Virtual Reality Program for Upper Extremity Stroke Rehabilitation
Published on: March 8, 2018
Nerve Tumors of the Upper Extremity
Sophia A Strike1, Mark E Puhaindran2
1Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Johns Hopkins Outpatient Center, 601 North Caroline Street, Suite 5252, Baltimore, MD 21287, USA.
Abstract:
Nerve sheath tumors of the upper extremity are among the common neoplastic pathologies encountered by hand surgeons. A majority of these tumors are benign schwannomas or neurofibromas and may be associated with neurofibromatosis. Clinical signs of malignant transformation include new onset of pain and rapid growth. Imaging characteristics, such as standardized uptake value greater than 4.0 on PET scan, may aid in the diagnosis of a malignant tumor. Surgical excision, often with intrafascicular dissection with nerve preservation, is recommended treatment of benign lesions. Wide surgical excision is recommended for malignant lesions.
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